DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment MP1 and try-1

DIOPT Version :9

Sequence 1:	NP_001303421.1	Gene:	MP1 / 40541	FlyBaseID:	FBgn0027930	Length:	400	Species:	Drosophila melanogaster
Sequence 2:	NP_494910.2	Gene:	try-1 / 173856	WormBaseID:	WBGene00006619	Length:	293	Species:	Caenorhabditis elegans

Alignment Length:	282	Identity:	88/282 - (31%)
Similarity:	126/282 - (44%)	Gaps:	65/282 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly   137 RVVGGNETTKREFPW-MALIEYTKPGNVKGHH-CGGSLINHRYVLTAAHCVS--AIPSDWELTGV 197
            |::||:|::...:|| :.|:...      ||| ||||||:..:|||||||.:  ..|:.:   .|
Worm    57 RLIGGSESSPHSWPWTVQLLSRL------GHHRCGGSLIDPNFVLTAAHCFAKDRRPTSY---SV 112

  Fly   198 RLGEWDASTNPDCTVGKNGRRDCNEPYVDYPVEERIP----HPQY----PGNSRDQLNDIALLRL 254
            |:|              ..|.....|:       |:.    ||.|    |.:     .|.|::|:
Worm   113 RVG--------------GHRSGSGSPH-------RVTAVSIHPWYNIGFPSS-----YDFAIMRI 151

  Fly   255 RDEVQYSDFILPVCLPTLASQHNNIFLGRKVVVAGWGRTETNFTSNIKLKAELDTVP---TSECN 316
            ...|..|....|:|||:|.:..|     |..||.|||.|....:.:.....|:. ||   |..|:
Worm   152 HPPVNTSTTARPICLPSLPAVEN-----RLCVVTGWGSTIEGSSLSAPTLREIH-VPLLSTLFCS 210

  Fly   317 QRYATQRRTVTTKQMCAGGVEG-VDSCRGDSGGPLLLEDYSNGNSNYYIAGVVSYGPTPCGLKGW 380
            .......|......:|||...| :|||:|||||||:..    .:.::.:.||||:| ..|...|.
Worm   211 SLPNYIGRIHLPSMLCAGYSYGKIDSCQGDSGGPLMCA----RDGHWELTGVVSWG-IGCARPGM 270

  Fly   381 PGVYTRVEAYLNWIE---NNVR 399
            ||||..|.:...||.   |.:|
Worm   271 PGVYGNVHSASTWINLEMNRLR 292

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
MP1	NP_001303421.1	CLIP	29..91	CDD:288855
		Tryp_SPc	137..394	CDD:214473	84/272 (31%)
		Tryp_SPc	138..397	CDD:238113	85/277 (31%)
try-1	NP_494910.2	Tryp_SPc	59..285	CDD:238113	84/271 (31%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100031
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900