DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment MP1 and CG43110

DIOPT Version :9

Sequence 1:	NP_001303421.1	Gene:	MP1 / 40541	FlyBaseID:	FBgn0027930	Length:	400	Species:	Drosophila melanogaster
Sequence 2:	NP_001246396.1	Gene:	CG43110 / 12798330	FlyBaseID:	FBgn0262570	Length:	483	Species:	Drosophila melanogaster

Alignment Length:	277	Identity:	84/277 - (30%)
Similarity:	128/277 - (46%)	Gaps:	50/277 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly   130 CGENFGDRVVGGNETTKREFPWMALIEYTKPGNVKGHH--CGGSLINHRYVLTAAHCVSAIPSDW 192
            ||:....:::.|:..:::...:||.|..|.       |  |||::|:..:|||.|||.|.
  Fly    28 CGKTPVPKIISGSNASQQSAQYMAGIFNTT-------HLLCGGTIIHEDFVLTVAHCKST----- 80

  Fly   193 ELTGVRLGEWDASTNPDCTVGKNGRRDCNEPYVDYPVEERIPHPQYPGNSRDQLNDIALLRLRDE 257
            :...||||.:                :.|.|.....|.|.|.||||..::  ..|||||::|...
  Fly    81 QTLFVRLGAY----------------NINHPTDQIRVIETIAHPQYSNST--YANDIALVKLERS 127

  Fly   258 VQYSDFILPVCLPTLASQHNNIFLGRKV---VVAGWGRTETNFTSNIKLKAELDTVPTSECNQRY 319
            |.::..|.|:|:      |.:..||:::   ...|||||.....|:|..:..::......|:...
  Fly   128 VIFNLNIQPICI------HLDATLGKQIRYYNAFGWGRTRNAEQSDILQRIFVNRTNPMICHLYL 186

  Fly   320 ATQRRTVTTKQMCAGGVEGVDSCRGDSGGPLLLEDYSNGNSNYYIAGVVSYGPTPC-GLKGWPGV 383
            .   .:...||:||...:| |:|.|||||||:.:....|.:.....|:.|||...| |:    |:
  Fly   187 G---MSPDPKQICATTDQG-DTCAGDSGGPLISKITYQGKNFDTQFGITSYGTRECNGV----GL 243

  Fly   384 YTRVEAYLNWIENNVRA 400
            ||.|..|..||.|.||:
  Fly   244 YTDVSQYSGWIANIVRS 260

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
MP1	NP_001303421.1	CLIP	29..91	CDD:288855
		Tryp_SPc	137..394	CDD:214473	77/262 (29%)
		Tryp_SPc	138..397	CDD:238113	79/264 (30%)
CG43110	NP_001246396.1	Tryp_SPc	35..254	CDD:214473	77/262 (29%)
CG43110	NP_001246396.1	Tryp_SPc	36..257	CDD:238113	79/264 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45463493
Domainoid	1	1.000	102	1.000	Domainoid score	I4289
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24260
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.940