DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment MP1 and CG42694

DIOPT Version :9

Sequence 1:	NP_001303421.1	Gene:	MP1 / 40541	FlyBaseID:	FBgn0027930	Length:	400	Species:	Drosophila melanogaster
Sequence 2:	NP_001188994.1	Gene:	CG42694 / 10178792	FlyBaseID:	FBgn0261584	Length:	512	Species:	Drosophila melanogaster

Alignment Length:	298	Identity:	69/298 - (23%)
Similarity:	111/298 - (37%)	Gaps:	94/298 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly   130 CGENFGDRVVGGNETTKREFP---WMALIEYTKPGNVKGHH--CGGSLINHRYVLTAAHCVSAIP 189
            ||....::.:     ||...|   |:|.|.       .|.|  |.||||:.::||:||.|:
  Fly    27 CGAPISNQSI-----TKLRQPQAGWLAHIS-------NGTHVLCSGSLISKQFVLSAAQCI---- 75

  Fly   190 SDWELTG---VRLGEWDASTNPDCTVGKNGRRDCNEPYVDYPVEERIPHPQYPGNSRDQL-NDIA 250
               ::.|   |:||..:|:.:|..                |.|...:    .|.:|..:| .||.
  Fly    76 ---DVHGKLFVQLGVSNATKSPHW----------------YTVSNVV----IPSHSGKRLQRDIG 117

  Fly   251 LLRLRDEVQYSDFILPVCLPTLASQHNNIFLGRKVVVAGWGRTETNFTSNIKLKAELDTVPTSEC 315
            ||:|...|.|:||:.|:|:....:..:.:.:.:....:.|.....|..:.:     |..:....|
  Fly   118 LLKLSQSVDYNDFVYPICIALNTNTLDMVKILQNFTTSAWLSKNKNPQTIV-----LSQLSRDRC 177

  Fly   316 NQRYATQRRTVTTKQMCAGGVEGVDSCRGDSGGPLL----------------LEDYSNGNSNYYI 364
            ....:   ..||.|::||..::..:||..|||..|.                :..|.||.|
  Fly   178 KLNLS---GNVTPKEICAASLQRNNSCFIDSGSALTQPIIQGSNIVREMLFGIRGYVNGRS---- 235

  Fly   365 AGVVSYGPTPCGLKGW---PGVYTRVEAYLNWIENNVR 399
                           |   |.:|..|...:.|||..|:
  Fly   236 ---------------WCSEPAIYIDVAECVGWIETVVQ 258

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
MP1	NP_001303421.1	CLIP	29..91	CDD:288855
		Tryp_SPc	137..394	CDD:214473	63/284 (22%)
		Tryp_SPc	138..397	CDD:238113	66/286 (23%)
CG42694	NP_001188994.1	Tryp_SPc	46..256	CDD:304450	63/270 (23%)
		Tryp_SPc	46..253	CDD:214473	60/267 (22%)
		Tryp_SPc	319..505	CDD:304450
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45463691
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24260
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.940