Protein Alignment Nepl11 and Ece1

DIOPT Version :9

• Sequence 1: NP_649449.1
• Gene: Nepl11 / 40540
• FlyBaseID: FBgn0037230
• Length: 592
• Species: Drosophila melanogaster
• Sequence 2: XP_006239337.1
• Gene: Ece1 / 94204
• RGDID: 620293
• Length: 769
• Species: Rattus norvegicus
• Alignment Length: 715
• Identity: 143/715 - (20%)
• Similarity: 252/715 - (35%)
• Gaps: 212/715 - (29%)

  Fly    30 SFSHNLEPYLDTSKQPCQDFYGYVCSH--SANLSETGRQRF----------QSLLK---ETDVAQ 79
            |..::::|.:|    |||||:.|.|..  .||....|..|:          |:::|   |...|.
  Rat   109 SILNSMDPTVD----PCQDFFSYACGGWIKANPVPDGHSRWGTFSNLWEHNQAIIKHLLENSTAS 169

  Fly    80 LMDMELQLINFFKSCESGRGVEALKGS---QLYRQSGGWPSLEPNKVNASQRTNQTQRWLGLLGY 141
            ..:.|.:...::::|.:...:|.|:..   :|..:.|||....|...:..|.|.|...
  Rat   170 ASEAEKKAQVYYRACMNETRIEELRAKPLMELIEKLGGWNITGPWAKDNFQDTLQVVT------- 227

  Fly   142 FHEVGAPYF--FETSVTMQSNKRLVVLQPDG----TRRNTLRKFEQ------------RVGEVLQ 188
            .|...:|:|  :.::.:..||..::.:...|    :|...|.|.|.            ::|::|.
  Rat   228 AHYRTSPFFSVYVSADSKNSNSNVIQVDQSGLGLPSRDYYLNKTENEKVLTGYLNYMVQLGKLLG 292

  Fly   189 SFGIEQSRAHV-------TALEVLSL-ERSRRDIVKADHVEDQVQFSYGNFKRIVFGNASLIRL- 244
            ....:..|..:       |||..::: :..|||                  :.:::...:...|
  Rat   293 GGDEDSIRPQMQQILDFETALANITIPQEKRRD------------------EELIYHKVTAAELQ 339

  Fly   245 ------DWDGYFRKLLGGKTPQASDTIVVKQLPRLVEYFALLQNTSMVRLLNW-IW-----TDYL 297
                  :|..:...:........|:.|||.....|.:...|:.:|....|.|: :|     |...
  Rat   340 TLAPAINWLPFLNAIFYPVEINESEPIVVYDKEYLRQVSTLINSTDKCLLNNYMMWNLVRKTSSF 404

  Fly   298 MD--IVDAD--------------------CHQLSETYAGDLYAHVVQRVTANRVE-----LAQMY 335
            :|  ..|||                    |...:|...|  :|.....|.|...|     .:::.
  Rat   405 LDQRFQDADEKFMEVMYGTKKTCLPRWKFCVSDTENNLG--FALGPMFVKATFAEDSKNIASEII 467

  Fly   336 SELGKAYTDQLGGSVWIDEISRQSSRQFLGNIMHTTLNGDERLDAAYHSILLGRRSLYRNLEKLR 400
            .|:.||:.:.|....|:||.:|:|::              |:.||.|:  ::|..:...:.::|.
  Rat   468 LEIKKAFEESLSTLKWMDEDTRRSAK--------------EKADAIYN--MIGYPNFIMDPKELD 516

  Fly   401 K------------FQRTRRLASHS----AQQVRRYA-----QMFAP-VNAFLGQ----------- 432
            |            |:...|..:.|    |.|:|:..     .|..| |||:...
  Rat   517 KVFNDYTAVPDLYFENAMRFFNFSWRVTADQLRKAPNRDQWSMTPPMVNAYYSPTKNEIVFPAGI 581

  Fly   433 -----HNLSTP--LNY----LLLGEFFSRSLVAAGSSSRTQG---AWRSSDSERRFAIFQQCV-- 481
                 :..|:|  ||:    :::|...:.:....|......|   .|..:.|...|....:|:
  Rat   582 LQAPFYTRSSPNALNFGGIGVVVGHELTHAFDDQGREYDKDGNLRPWWKNSSVEAFKQQTECMVQ 646

  Fly   482 --------GKQTNAIDLLLSLLAQ----RQALSAYGQWLATQAGLVERVDAVLAAGSSKMSLQRL 534
                    |:..|....|...:|.    :.|..||..|:....  .|::...|...|:     :|
  Rat   647 QYNNYSVNGEPVNGRHTLGENIADNGGLKAAYRAYQNWVKKNG--AEQILPTLGLTSN-----QL 704

  Fly   535 FFVTSLLVDC------RSELGAL----QQDRKRQVTHATLRNSPEFLEAFRCRPGDVLYPQDQRC 589
            ||:....|.|      .|..|.:    ...|.|.:  .:|.||.||.|.|||..|..:.|: .:|
  Rat   705 FFLGFAQVWCSVRTPESSHEGLITDPHSPSRFRVI--GSLSNSKEFSEHFRCPLGSPMNPR-HKC 766

  Fly   590  589
              Rat   767  766

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nepl11	NP_649449.1	GluZincin	45..589	CDD:301352	139/698 (20%)
Ece1	XP_006239337.1	PepO	105..769	CDD:226118	143/715 (20%)
		M13	118..767	CDD:189000	141/706 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3590
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900