Protein Alignment Nepl11 and Nepl18

DIOPT Version :10

• Sequence 1: NP_649449.1
• Gene: Nepl11 / 40540
• FlyBaseID: FBgn0037230
• Length: 592
• Species: Drosophila melanogaster
• Sequence 2: NP_651643.1
• Gene: Nepl18 / 43410
• FlyBaseID: FBgn0039611
• Length: 682
• Species: Drosophila melanogaster
• Alignment Length: 747
• Identity: 157/747 - (21%)
• Similarity: 257/747 - (34%)
• Gaps: 245/747 - (32%)

  Fly     8 VLWI---------------AGIAYGQDDL-------LRVETELLSFSHNLEPYLDTSKQPCQDFY 50
            |||:               ||..:. |||       :.|:.::......::|.:    .||.|||
  Fly     6 VLWLCLLVAIVPAMAKPSDAGDPFA-DDLTSDYAKKIIVQAKVAEMKTMMKPEV----SPCDDFY 65

  Fly    51 GYVCS--HSAN---------------LSETGRQRFQSLLKETDVAQLMDMELQLINFFKSCESGR 98
            .:.|.  |..|               :|:...:|.|.||:..|:...::.::|  .|:.||....
  Fly    66 THACGNWHRHNPAQLLGDVMTDNFKLISKGFDRRLQRLLRANDLQSELEKKMQ--RFYMSCNLVH 128

  Fly    99 GVEA---LKGSQLYRQSGGWPSLEPNKVNASQRTNQTQRWLGLLGYFHEVGAPYFF--------- 151
            ..:.   |....:.|:.|..|:|    |.|...::....|..:....|:.|.....
  Fly   129 RDDVHYKLALENVIREYGTLPAL----VGAQWNSSDFSWWRTVAQIQHKYGKQIIIGLEIMHDIR 189

  Fly   152 ETSVTMQSNKRLVVLQPD----GTRRNTLRKFEQRVGEVLQSFGIEQSRAHVTALEVLSLERSRR 212
            .|||     .|:.:.|||    .||...|.:..:...::.|.||:..|.|..||.::..|||:
  Fly   190 NTSV-----NRVYISQPDFKTINTRLTNLMEEVRTSMDLQQYFGLSSSVAKHTAEQLTELERT-- 247

  Fly   213 DIVKADHVEDQVQFSYGNFKRIVFGNASL-----------------IRLDWDGYFRKLLGGKTPQ 260
                         ||.|.     .|.|:|                 ..|::..:...:||
  Fly   248 -------------FSSGG-----SGAATLQESLSLYTVADLQEKYSDHLNFTEFLGLILG----- 289

  Fly   261 ASDTIVVKQLPRLV-----EYF--ALL--QNTSMVRLLNWI-W---TDYLMDIVDAD----CHQL 308
                  .:.:|:.:     ||.  |||  ::|.:....|:: |   .|:|:|....|    |.:.
  Fly   290 ------EENIPKSLYIYDEEYLDKALLTMRSTPLATQANYVLWKLLEDFLVDAQPKDMVKWCTES 348

  Fly   309 SETYAGDLYAHVVQRVTANRVELAQMYSELGKAYTDQLGGSV----------WIDEISRQSSRQF 363
            ::.|.|.|..|.|.:    |.....:.||:.|.: ||:.|..          ||...:|..:.:.
  Fly   349 TKKYFGKLAEHAVYK----RYRNPDVESEVHKIW-DQIKGIFRQRLLGDKLDWISNATRTLAIEK 408

  Fly   364 LGNIMHTTLNG--DERLDAAYHSILLGRRSLYRNLEKLRKFQRTRRLASHSAQQVRRYAQMFAPV 426
            |.. ||..:|.  :|..:..|..:.:.|.:...|:::|        |.:...:.|.|..|....|
  Fly   409 LER-MHLNINSYDEENFENVYGEVFIDRLNYVSNVQQL--------LIAKGIRFVARINQPADSV 464

  Fly   427 NA--FLG--------QHNLSTP----------------------LNYLLLGEFF------SRSLV 453
            :|  .||        ::|::.|                      |.|||..|..      .|...
  Fly   465 DATELLGFTPAYNIQENNITIPVALLQPRYFWGDQYPEALKYATLGYLLAHEMLHGFDDDGRQYD 529

  Fly   454 AAGSSSRTQGAWRSSDSERRFAIFQQCVGKQTNAIDLLLSLLAQ--------------RQALSAY 504
            |:|:.:    .|....|...|...::|...|.:......|.|.:              :.|.:||
  Fly   530 ASGNLA----PWWDLKSRYEFEERRKCFQAQYHEYQYGGSKLPESKDQSENIADSGGLKLAYAAY 590

  Fly   505 GQWLATQAGLV---ERVDAVLAAGSSKMSLQRLFFV--TSLLVDCRSEL---GALQQDRKRQVTH 561
            ..||..|:..|   |.::.:      ..:.::|||:  ..||.|....|   ...|.||     |
  Fly   591 ELWLGQQSEEVLQRETMEGL------PFNSRQLFFLGYAQLLCDDVQFLFQPWVSQSDR-----H 644

  Fly   562 A--------TLRNSPEFLEAFRCRPGDVLYPQ 585
            |        .|.|..||...|.|.....:.|:
  Fly   645 APSKYRVIGPLSNFQEFPWVFNCSQSAPMDPE 676

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nepl11	NP_649449.1	GluZincin	45..590	CDD:472708	147/688 (21%)
Nepl18	NP_651643.1	M13	58..679	CDD:341056	147/694 (21%)