Protein Alignment Nepl11 and Nepl16

DIOPT Version :9

• Sequence 1: NP_649449.1
• Gene: Nepl11 / 40540
• FlyBaseID: FBgn0037230
• Length: 592
• Species: Drosophila melanogaster
• Sequence 2: NP_001097912.1
• Gene: Nepl16 / 43014
• FlyBaseID: FBgn0039277
• Length: 752
• Species: Drosophila melanogaster
• Alignment Length: 688
• Identity: 128/688 - (18%)
• Similarity: 231/688 - (33%)
• Gaps: 230/688 - (33%)

  Fly    34 NLEPYLDTSKQPCQDFYGYVC------SHSANLSETGRQRFQSLLKETDVAQLMDMELQLI---- 88
            :::..|:.:|.||.:|..:.|      .:..||.|.|..:     |..|...|...:.:::
  Fly   166 SIQARLNWNKDPCTEFKKFSCWRNTPNKNITNLIEMGNSQ-----KSVDSQMLYLFQNKIMNGSF 225

  Fly    89 ----NFFKSCESGRGVEALKGS----QLYRQSGGW---PSLEPNKVNASQRTNQTQRWLGLLGYF 142
                |.|:||     ::....|    :::...||:   .|:.|:.:            ..|:...
  Fly   226 GILHNLFESC-----LQQTTNSTVMHRIFDSLGGYLPVGSVGPSSI------------APLIAKI 273

  Fly   143 HEVGAPYFFETSVTMQSNKR---LVVLQPDGTRRNTLRK-------------------------- 178
            :::|.....:....:...:|   |:::....|....|.:
  Fly   274 YDLGPSPLVDLYHDLSYGRRPHILLIISGPSTSSTILERKIRWMSPKAPPSRIRQGVPKLLADLI 338

  Fly   179 ---------FEQRVGEVLQSFGIEQSRAHVTALEVLSLERSRRDIVKADHVEDQVQFSYGNFKRI 234
                     :.|||.|....|      ..:..|..|.:|.|||                |.:...
  Fly   339 ENFLPYFVSYAQRVSEKDTIF------EFIKDLNKLQVEHSRR----------------GFWDST 381

  Fly   235 VFGNASLIR-----LDWDGYFRKLLGGKTPQA-SDTIVVKQLPRL--VEYF-----ALLQNTSMV 286
            |..|.|.::     |:|     .||   .||. |..|||:....|  :|||     ..:.:.|::
  Fly   382 VLYNVSSLQDLYPVLNW-----TLL---IPQNWSGPIVVRNSDYLKALEYFLTKYPTRVAHNSLL 438

  Fly   287 RL--LNWIWTDYLMDIVDADCHQLSETYAGDLYA--HVVQ------RVTANRVELAQMYSELGKA 341
            .|  |..:..||....|   |.:.:.....:|.:  ::.|      :.|..|.|:  ::..| ||
  Fly   439 LLSALQILPRDYPSPEV---CTRSTMWALPELSSSLYIAQHSSEDLKDTTKRAEI--IFKSL-KA 497

  Fly   342 Y---TDQLGGSVWIDEISRQSSRQFLGNIMHTT--LNGDERLDAA----YHSILLGRRSLYRNLE 397
            :   ...|.|:..:...:.:...|......:||  |...:.|:..    :.:||    .:|:. .
  Fly   498 HLKRAPSLKGAALVKLSALKIQSQTWEGFSNTTDLLKSLQPLNITSECWFQNIL----EIYKK-N 557

  Fly   398 KLRKFQRTRRLASHSAQQVRRYAQMF---------APVNAFLGQH-NLSTP--LNYLLLGEFFSR 450
            ||.....:....||.|......:.:|         .|::..|..: |...|  |:|..:|...::
  Fly   558 KLEPNDISLNGGSHDAWAYPIVSTIFYDTLSHSIVVPLSVILIPYFNAVLPPYLHYASVGVSIAK 622

  Fly   451 SLVAAGSSSRTQGAWRSSDSERRFAIFQQCVGKQTN------AIDLLL----SLLAQRQALSAYG 505
            .::.:.:.|..:.|.|             ||....|      .:|:|:    ..::....||..|
  Fly   623 EILRSITKSFDEKAMR-------------CVPHSVNIFSNYSRMDILIHSGGMQISYHSMLSLTG 674

  Fly   506 --QWLATQAGLVERVDAVLAAGSSKMSLQRLFFVTSLLVDCRSELGALQQDRKRQVTHATLRNSP 568
              :.:|...||             .::..::||:.|....| :|...|..|          .|:|
  Fly   675 PIKGMARLPGL-------------NLTPTQIFFLVSAQELC-AESNYLGID----------TNAP 715

  Fly   569 EF--------------LEAFRCRPGDVLYPQDQRCNPL 592
            ||              .|.|:|..|.::..| :.||.|
  Fly   716 EFDNILGWLVAQGGSATEVFKCPSGSMINVQ-KTCNVL 752

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nepl11	NP_649449.1	GluZincin	45..589	CDD:301352	123/672 (18%)
Nepl16	NP_001097912.1	GluZincin	176..749	CDD:301352	123/673 (18%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3590
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11733
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.910