Protein Alignment Nepl11 and Ece2

DIOPT Version :10

• Sequence 1: NP_649449.1
• Gene: Nepl11 / 40540
• FlyBaseID: FBgn0037230
• Length: 592
• Species: Drosophila melanogaster
• Sequence 2: XP_038944493.2
• Gene: Ece2 / 408243
• RGDID: 1303039
• Length: 789
• Species: Rattus norvegicus
• Alignment Length: 674
• Identity: 135/674 - (20%)
• Similarity: 225/674 - (33%)
• Gaps: 190/674 - (28%)

  Fly     6 LAVLWIAGIAYGQDDL---------LRVETELLSFSHNLEPYLDTSKQPCQDFYGYVCSH--SAN 59
            |..||   :.|.:|.:         :||..::|.       .||....||||||.:.|..  ..|
  Rat   156 LVALW---VQYHRDPVHSTCITEACIRVAGKILE-------SLDRGVSPCQDFYQFSCGGWIRRN 210

  Fly    60 LSETGRQRFQS--------------LLKETDVAQLMDMELQLINFFKSCESGRGVEALKG---SQ 107
            ...:||.|:.:              ||:.:......:.|.:..:|:.||.....:|.|..   ..
  Rat   211 PLPSGRSRWNTFNSLWDQNQAILKHLLENSTFNSSSEAERKTRSFYLSCLHLERIEKLGAKPLQD 275

  Fly   108 LYRQSGGW----PSLEPNKVNASQRTNQTQRWLGLLGYFHEVGAPYF--FETSVTMQSNKRLVVL 166
            |..:.|||    |..|.|.:...:....|.|           .||:|  :..:.:..||..::.:
  Rat   276 LIDKIGGWNITGPWDEDNFMEVLKAVAGTYR-----------AAPFFTVYVGADSKSSNSNIIQV 329

  Fly   167 QPDG-------------TRRNTLRKFEQRVGEVLQSFGIEQSRAHVTALEVLSLE---------- 208
            ...|             .....|..:...:.|:....|.:.:.......:||.||
  Rat   330 DQSGLFLPSRDYYLNRTANEKVLAAYLDYMVELGMLLGGQPTSTRAQMQQVLELEIQLATITVPQ 394

  Fly   209 RSRRDIVKADHVEDQVQFSYGNFKRIVFGNASLIRLDWDGYFRKLLGGKTPQASDTIVVKQLPRL 273
            ..|||..|..|     :.|....:.:.      ..:||..:...||.......|:.:||.....|
  Rat   395 DQRRDEEKIYH-----KMSISELQTLA------PSMDWLEFLSFLLSPLELGDSEPVVVYGTEYL 448

  Fly   274 VEYFALLQNTSMVRLLNW-IW------TDYLMDIVDADCHQLSETY------------------- 312
            .:...|:..|....|.|: ||      |..|....:....:|.||.
  Rat   449 QQVSELINRTEPSILNNYLIWNLVQKTTSSLDQRFETAQEKLLETLYGTKKSCTPRWQTCISNTD 513

  Fly   313 ------AGDLYAHVVQRVTANR--VELAQ-MYSELGKAYTDQLGGSVWIDEISRQSSRQFLGNIM 368
                  .|.|:.    :.|.:|  .|:|: |.||:..|:.:.|...||:||.:|.::::....|.
  Rat   514 DALGFALGSLFV----KATFDRQSKEIAEGMISEIRAAFEETLENLVWMDEKTRLAAKEKADAIY 574

  Fly   369 HTTLNGD-----ERLDAAYHSILLGRRSLYRNLEKLRKFQRTRRLASHSAQQVRR------YAQM 422
            ......|     ..||..|....:...|.::|:..|..|.     |...|.|:|:      ::..
  Rat   575 DMIGFPDFILEPRELDDVYDGYEVSEDSFFQNMLNLYNFS-----AKVMADQLRKPPSRDQWSMT 634

  Fly   423 FAPVNAF------------------LGQHNLSTPLNY----LLLGEFFSRSLVAAGSSSRTQG-- 463
            ...|||:                  ...||....||:    :::|...:.:....|.....:|
  Rat   635 PQTVNAYYLPTKNEIVFPAGILQAPFYAHNHPKALNFGGIGVVMGHELTHAFDDQGREYDQEGNL 699

  Fly   464 -AWRSSDSERRFAIFQQCV----------GKQTNAIDLLLSLLAQ----RQALSAYGQWLATQAG 513
             .|..::|...|.....|:          |::.|.:..|...:|.    :.|.:||..|| .:.|
  Rat   700 RPWWQNESLTAFQNHTACMEEQYNQYQVNGERLNGLQTLGENIADNGGLKAAYNAYKAWL-RKHG 763

  Fly   514 LVERVDAVLAAGSSKMSLQRLFFV 537
            ..:.:.||      .::..:||||
  Rat   764 EEQPLPAV------GLTNHQLFFV 781

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nepl11	NP_649449.1	GluZincin	45..590	CDD:472708	125/626 (20%)
Ece2	XP_038944493.2	None