Protein Alignment Nepl11 and Nep3

DIOPT Version :9

• Sequence 1: NP_649449.1
• Gene: Nepl11 / 40540
• FlyBaseID: FBgn0037230
• Length: 592
• Species: Drosophila melanogaster
• Sequence 2: NP_001245775.1
• Gene: Nep3 / 33005
• FlyBaseID: FBgn0031081
• Length: 786
• Species: Drosophila melanogaster
• Alignment Length: 693
• Identity: 132/693 - (19%)
• Similarity: 242/693 - (34%)
• Gaps: 173/693 - (24%)

  Fly    39 LDTSKQPCQDFYGYVCSH--SANLSETGRQRFQSLLKETDVAQLM--------------DMELQL 87
            :|.:..||.|||||.|:.  ..|....|:..:.:..|...:.||:              |.|.:.
  Fly   119 IDVTVDPCDDFYGYSCNQWIKNNPIPEGKSTWGTFGKLEQMNQLIIRNVLEKPAKSFKSDAERKA 183

  Fly    88 INFFKSC-ESGRGVEALKG---SQLYRQSGGWPSLEPNKVNASQRTNQTQRW-----LGLLGYFH 143
            ..:::|| ::...:|.|..   :.|..|.|||        |.::.......|     |.:|...:
  Fly   184 KVYYESCLDADEHMEKLGAKPMNDLLLQIGGW--------NVTKSGYNVANWTMGHTLKILHNKY 240

  Fly   144 EVGAPYFFETSVTMQSNKRLVVLQPDG---------------TRRNTLRKFEQRVGEVLQSFGIE 193
            .....:.:......:::.|.|:....|               ..|..|.::.:.:.:|....|..
  Fly   241 NFNCLFGWAIGEDDKNSSRHVIQIDQGGLTLPTADYYNNKTDNHRKVLNEYIEYMTKVCVLLGAN 305

  Fly   194 QSRAHVTALEVLSLERSRRDIV--KADHVEDQVQFSYGNFKRIVFGNASLIR-LDWDGYF---RK 252
            :|.|....:.|::.|:...:|.  ..|...::..:.....:::    :.|.. |:|..:|   .:
  Fly   306 ESDARAQMIGVINFEKKLANITIPLEDRRNEEAMYHPMQLRQL----SKLAPFLNWTDHFDNAMQ 366

  Fly   253 LLGGKTPQASDTIVVKQLP----RLVEYFALLQNT--SMVRLLNWIWTDYLMDIVDADCHQLSET 311
            ::|.:.  ..|.:||...|    .|.:....::.|  ..:.|.|::....:..:.........:.
  Fly   367 MVGRRV--TDDEVVVVYAPDFLKNLSDIILKMEQTEEGKITLNNYLVWQAVRTLTSCLSKPFRDA 429

  Fly   312 YAG------------DLYAHVVQRVTANRVELA-------------------QMYSELGKAYTDQ 345
            |.|            :::.:.|.. |.|.|..|                   ||.:|:.:|:...
  Fly   430 YKGVRKALMGSDGGEEIWRYCVSD-TNNVVGFAVGAIFVRQAFHGESKPAAEQMIAEIREAFKMN 493

  Fly   346 LGGSVWIDEISRQSSRQFLGNIMHTTLNGDERLDAAYHSILLGRRSLYRNLEKLRKFQRTRRLAS 410
            |....|:|:.:|:.:.:....|.......|..||    .:.|.::....|:.....|:...::|.
  Fly   494 LQNLTWVDKQTREKAIEKANQISDMIGFPDYILD----PVELDKKYAELNITPNAYFENNIQVAI 554

  Fly   411 HSA--------QQVRRYAQMFAP--VNAFLGQHN---------LSTP---------LNYLLLGEF 447
            ::.        |.|.:......|  |||:.....         |.||         ||:..:|..
  Fly   555 YNLKSNLKRLDQPVNKTNWGMTPQTVNAYYTPTKNQIVFPAGILQTPFFDINNPKSLNFGAMGVV 619

  Fly   448 FSRSLVAA-----------GSSSRTQGAWRSSDSERRFAIFQQCVGKQTNAIDLLLSLLAQRQAL 501
            ....|..|           |:.:|    |..|.|..||....:|:.:|.:...:....|..:|.|
  Fly   620 MGHELTHAFDDQGREYDKFGNINR----WWDSKSIERFNEKSECIARQYSGYKMNGRTLNGKQTL 680

  Fly   502 SAYGQWLATQAGLVERVDA-----------VLAAGSSKMSLQRLFFVTSLLVDCRS---ELGALQ 552
               |:.:|...||.....|           :|......::..:||||:...|.|.|   |...||
  Fly   681 ---GENIADNGGLKAAYHAYQRTKSDRDVDILKLPGLNLTHSQLFFVSFAQVWCSSTTDETNLLQ 742

  Fly   553 QDRKRQVTHA--------TLRNSPEFLEAFRCRPGDVLYPQDQ 587
            .::.   .|:        ||.|..||.|.|:|:||..:.|.::
  Fly   743 MEKD---PHSPSQFRVIGTLSNMKEFAEVFQCKPGKRMNPTEK 782

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nepl11	NP_649449.1	GluZincin	45..589	CDD:301352	131/687 (19%)
Nep3	NP_001245775.1	M13	123..784	CDD:189000	131/689 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3590
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11733
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.910