Protein Alignment Nepl11 and Nepl3

DIOPT Version :10

• Sequence 1: NP_649449.1
• Gene: Nepl11 / 40540
• FlyBaseID: FBgn0037230
• Length: 592
• Species: Drosophila melanogaster
• Sequence 2: NP_608904.1
• Gene: Nepl3 / 326172
• FlyBaseID: FBgn0031678
• Length: 629
• Species: Drosophila melanogaster
• Alignment Length: 695
• Identity: 139/695 - (20%)
• Similarity: 232/695 - (33%)
• Gaps: 198/695 - (28%)

  Fly     6 LAVLWIAGIAYGQDDLLRVETELLSFSHNLE------PYLDTSKQPCQDFYGYVCSHSANLS--- 61
            |::.|:         ||.:.:.:.|.:.|||      ..:|...:||.:||.   |...||.
  Fly     8 LSLSWL---------LLLLCSTVCSANPNLEIMKRMLDDMDEKVEPCHNFYN---SSQKNLKWHA 60

  Fly    62 -ETGRQRFQSLLK--ETDVAQLMDMELQLINFFKSCESGRGVEALKGSQLYR--QSGGWPSLEPN 121
             .|...:||.|..  |.:|.:....|.:|...:|.|.:......|:..:|.:  :...||.|.|
  Fly    61 FATVSDQFQLLFDGIENEVFEKHSFEEKLQRLYKICSTMERPSLLRYFELVKPGEDLNWPFLTP- 124

  Fly   122 KVNASQRTNQTQRWLGLLGYFHEVG-APYFFETSVTMQSN----KRLVVLQPDGTRRNTLRKFEQ 181
              ...:...:..:|:..|......| ....|..|:....|    :.:||.:         :|::.
  Fly   125 --RGGKWPKEKFQWMEALARLRRYGFNDIMFGMSIRQDPNSDSGQPIVVFE---------KKYDS 178

  Fly   182 --RVGEVLQSFGIEQSRAHVTALEVLSLERSRRDIVKADHVEDQVQFSYGNFKRIVFGNASLIRL 244
              |..|.||:.|:...    .|.|:..|:.:.:::.|:|...:.........|||..|...:..:
  Fly   179 LFRFIESLQNIGLPPK----LAKEIAPLDNAIQEMYKSDMKFEHYARDAAPVKRISLGQLEIYGV 239

  Fly   245 DWDGYFRKLLGGKTPQASDTIV-VKQLPRLVEYFALLQN-----TSMVRLLNWI---WTDYLM-- 298
            ....|...:.|  .|.:.|.:| |:.|    .|...|||     .|.| :.|::   ::.|:|
  Fly   240 SLTKYLEIVFG--RPFSPDFVVHVENL----YYLRGLQNLMTAVPSQV-VANYLTARFSFYIMFT 297

  Fly   299 -----DIVDADCHQLSETYAGDLYAHVVQRVTANRVELAQMYSELGKAYTDQLGGSVWIDEISRQ 358
                 |.......|..| :|.:|   :.:.....|.:|....::.||.:          |.|.:|
  Fly   298 FMKHGDSCVTTMRQSME-FASNL---LFEERILGRKKLRSYQNQAGKIF----------DAIRQQ 348

  Fly   359 SSRQFLGNI----------MHTTLNG-----------------------------DERLDAAYHS 384
            .:.:...|:          :...|||                             ||.|..|:..
  Fly   349 LNIRLERNVLKLPPAEISLLQKKLNGLSLSIGNLPGKAGHRRFVTRYYKELEFADDEELATAHLK 413

  Fly   385 ILLGRRSLYRNLEKLRKFQRTRRLASHSAQQVRRYAQMFAPVNAFLGQHNLSTPLNYLLLGEFFS 449
            :|..|.....:|.....| :.||...||           .|::.|..:.......|.:.:...|
  Fly   414 VLEHRTRAELSLLDQPNF-KDRRYMLHS-----------YPISNFFFETAYEENGNTIYVAYDF- 465

  Fly   450 RSLVAAGSSSRTQGAWRSSDSERRFAI-------FQQCVGKQTNAIDLL------------LSLL 495
              |..|.....:...::.:....||.:       ...|...:.|.:.|.            :|..
  Fly   466 --LADASFDPDSHDIFKVTPLGIRFGLEMLKSFDLFNCKHHKVNMLQLFDDNQITTAGDECVSAW 528

  Fly   496 AQRQALSAYGQWLATQAGLVERVDAVLAAGS---------SKMSLQRLFFVT------------- 538
            .|...||...|:|.. ..||.  :|..|.||         :.|||:.|||..
  Fly   529 TQDNLLSQRDQYLVV-LHLVH--EAYFAEGSKFSQRQPNFTTMSLRELFFFRFGQSSFGQTLYFG 590

  Fly   539 SLLVDCRSELGALQQDRKRQVTHATLRNSPEFLEAFRC-RPGDVL 582
            |..|:..|.:.:|.:             .|.|:..|.| .||:.|
  Fly   591 SDFVEGGSPINSLTR-------------LPVFVRTFNCLAPGEQL 622

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nepl11	NP_649449.1	GluZincin	45..590	CDD:472708	130/650 (20%)
Nepl3	NP_608904.1	GluZincin	42..>434	CDD:472708	86/432 (20%)