Protein Alignment Nepl11 and Nep6

DIOPT Version :10

• Sequence 1: NP_649449.1
• Gene: Nepl11 / 40540
• FlyBaseID: FBgn0037230
• Length: 592
• Species: Drosophila melanogaster
• Sequence 2: NP_572831.2
• Gene: Nep6 / 32234
• FlyBaseID: FBgn0030425
• Length: 655
• Species: Drosophila melanogaster
• Alignment Length: 686
• Identity: 137/686 - (19%)
• Similarity: 229/686 - (33%)
• Gaps: 204/686 - (29%)

  Fly    40 DTSKQPCQDFYGYVCSH-SANLSETGRQRFQSLLKETDVAQ--LMDMELQLINFFKSCESGRGVE 101
            |...:||::|:.|.|.: .:|.|       |.:|...|:..  :.:::||||.:.:...|.....
  Fly    37 DAEVKPCENFHQYACGNWYSNTS-------QRILGAHDMRSKWVANLKLQLIRYLEESSSTDSFS 94

  Fly   102 A-------------------LKGSQ-------LYRQSGGWPSLEPNKVNASQRTNQTQRWLGLLG 140
            |                   |.|..       |.|....:|.|       :..|..:..|:....
  Fly    95 ANTSVTTSTAQLGTLYRCCLLSGQSIRTYTDALSRSGANFPLL-------ANHTGGSFDWVLANA 152

  Fly   141 YFHEVGAPYFFETSVT---MQSNKRLVVLQPDG----TRRNTLRKF--EQRVGEVLQSFGIEQSR 196
            .....||...:...|.   ..:::|:..:.|..    .|.:.|.:|  ::.:..:|...|:...|
  Fly   153 ALRTYGAQGLWRLLVKDNWQSADQRIFYMLPPKFDLLGRDDELNEFLYQRYLKILLLELGLRVRR 217

  Fly   197 AHVTALEVLSLERSRRDIVKADHVEDQVQFSYGNFKRIVFGNASLIRLDWDGYFRKLLGG----- 256
            |.:.|.::::.|:|.:.::..|..:..|.....:.|.:   .:.|.||:...||..:|.|
  Fly   218 AALLAEKLVAFEKSLQKLLPNDAEQTLVLRKPQSLKDL---ESQLPRLELKRYFETILEGIDWDS 279

  Fly   257 KT-----------------------PQASDTIVVKQLPRLVEYFALL---------QNTSMVRLL 289
            ||                       |....|.::.|||   .||.|.         |....:..|
  Fly   280 KTLLLVADLDYLQGLQRLLAEHTSDPMVLSTWLLLQLP---AYFELRLHDDDKLGNQRNHCLEQL 341

  Fly   290 NWIWTDYL----MDIVDADCHQLSETYAGDLYAHVVQRVTANRVELAQMYSEL------------ 338
            ..:....|    |.:|      |.|:|. |:|...:|::.....:|.|.: ||
  Fly   342 RKLMPGQLGRLQMQLV------LGESYQ-DVYDTAIQQIAVLFRDLKQQF-ELVLNETEVFNEDL 398

  Fly   339 -------------------------GKAYTDQLGGSVWIDEISRQSS------RQFLGNIMHTTL 372
                                     |...|.||||:...:.:....|      ||..|..: |::
  Fly   399 VTRNLARDKLRAMRLLTPRLQDPINGGPGTPQLGGNCDANLLQLSLSQAKLEYRQVFGEPV-TSV 462

  Fly   373 NGDERLDAAYHSILLGRRSLYRNLEKLRKFQRTRRLASHSAQQVRRYAQMFAPVNAFLGQHNLST 437
            ..|.....||:.:.|.|..|...|......|          ||..:.|...|.::|.||
  Fly   463 PADPLSVNAYYRLKLNRIELPLGLMATPLIQ----------QQCSKEADTRAKLSAGLG------ 511

  Fly   438 PLNYLLLGE----FFSRSLVAAGSSSRTQGAWRSSDSERRFAIFQQC-VG-KQTNAIDLLLSLLA 496
               |:|..|    |....|....:.....|.| |:.:..||.:...| :| :.:||...:...:|
  Fly   512 ---YILAHEMVHAFDLDGLNYDATGQLANGQW-SARAIIRFGLRAGCYLGVRYSNATLTVNENIA 572

  Fly   497 Q----RQALSAYGQWLATQAGLVERVDAVLAAGSSKMSLQRLFFVTSLLVDC---RSELGALQQD 554
            .    |.||..|..                .:|::.:   |.|||......|   .|..|..|..
  Fly   573 DTEGLRLALDTYRH----------------RSGATNL---RTFFVAFAQNWCGTVASTSGLSQHA 618

  Fly   555 RKRQVTHATLRNSPEFLEAFRCRPGDVLYPQDQRCN 590
            ...:..:..:.|.|||.:.|.|:....:.|.: :|:
  Fly   619 GHAERVNNVVGNMPEFGDTFECKATSQMNPVN-KCH 653

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nepl11	NP_649449.1	GluZincin	45..590	CDD:472708	135/679 (20%)
Nep6	NP_572831.2	M13	40..653	CDD:341056	135/681 (20%)