Protein Alignment Nepl11 and Kel

DIOPT Version :9

• Sequence 1: NP_649449.1
• Gene: Nepl11 / 40540
• FlyBaseID: FBgn0037230
• Length: 592
• Species: Drosophila melanogaster
• Sequence 2: NP_001178540.1
• Gene: Kel / 297025
• RGDID: 1565470
• Length: 713
• Species: Rattus norvegicus
• Alignment Length: 694
• Identity: 146/694 - (21%)
• Similarity: 236/694 - (34%)
• Gaps: 206/694 - (29%)

  Fly    42 SKQPCQDFYGYVCSHSAN--------LSETGRQRFQSLLKETDVAQLMDMELQLINFFKSCESGR 98
            |..||.||:.:.| ..||        |:|..:.|...||:......|...|.:...|:.||....
  Rat    77 SAAPCTDFFSFAC-EKANGTSNSFQALAEENKSRLWKLLEAPGSWHLESGEEKAFQFYNSCMDTD 140

  Fly    99 GVEALKGS----QLYRQSGGWPSLEPNKVNASQRTNQTQRW--------LGLL-----------G 140
            .:|| .|:    |:.::.|||              |.:..|        |.||           .
  Rat   141 AIEA-SGTGPLVQIIKELGGW--------------NISGNWTFFDFNQNLRLLMSQYGHFPFFRA 190

  Fly   141 YFHEVGAPYFFETSVTMQSNKRL-VVLQPDGTRR---NTLRKFE---QRVGEVLQSFGIEQSRAH 198
            |.|...||.  .|.:........ ::||.|..::   ..||::.   .|:|.:|.| ..::::.|
  Rat   191 YLHPHPAPP--HTPIIQIDQPEFDILLQQDQEQKVYAQILREYVTYLNRLGTLLGS-NPQEAQQH 252

  Fly   199 VT--------ALEVLSLERSRRDIVKADHVE--DQVQFSYGNFKRIVFGNASLIRLDWDGYFR-- 251
            .:        ..:.|..::.::...|..||.  |.:|             .....:||....:
  Rat   253 ASWSIVFTSRLFQFLRPQQQQQAQDKLFHVVTIDALQ-------------EMAPAIDWLSCLQAI 304

  Fly   252 ----KLLGGKTPQASDTIVVKQLPRLVEYFALLQNTSMVRLLNWIWTDYLMDIVDA--------- 303
                .|...:|.|..|...::.:.:|||. .||.::.:::      :..::.:||.
  Rat   305 FTPMSLSPSQTLQVHDLDYLRNMSQLVEE-GLLNHSEIIQ------SYMILGLVDTLSPALATKF 362

  Fly   304 ---------------------------DC-HQLSETYAGDLYAHVVQRVTANRVELA--QMYSEL 338
                                       .| .|....:...|.|..|.......:..|  ::::|:
  Rat   363 QEARRELTQKLRKLKERPPLPAYPRWMKCVEQTGSFFEPTLAALFVHEAFGPSIRSAAMELFAEI 427

  Fly   339 GKAYTDQLGGSVWIDEISRQSSRQFLGNI----------MHTTLNGDERLDAAYHSILLGRRSLY 393
            ..|...:|....||.|.:|:.:...|..:          :.|.:...|     |..|.||...|.
  Rat   428 KDAVIVRLKKLSWISEETRKEALNKLTQLQVEMGAPKRALKTEMAKQE-----YSDIQLGPSFLQ 487

  Fly   394 RNLEKLRKFQRTRRLASHSAQQVRRYAQMF-------AP--VNAF--LGQHNLSTPLNYLLLGEF 447
            ..|..:|..|         .::||.:.|.|       :|  |:|:  :..|.:..|.. ||...|
  Rat   488 SFLSCVRSLQ---------GRKVRSFLQPFPYHRWQKSPWSVSAYYSVPDHVVVFPAG-LLQPPF 542

  Fly   448 FSRSLVAAGSSSRTQGAWRSSDSERRFAIFQQ------CVGKQTNAIDLLLSLLAQRQA------ 500
            |......|.:.    ||..|..:.:...||.|      |....|.|:...|..|..|.|
  Rat   543 FHPGYPRAVNF----GAVGSIMAHKLLHIFFQFLLPGGCPACDTRALQEALLCLEHRYAAFPLPS 603

  Fly   501 LSAY--------------GQWLATQA---GLVERVDAVLAAGSSKMSLQRLFFVTSLLVDCRSEL 548
            :|::              |..:|.||   .:.||. ..|...:.::|..:|||.:...|.||..:
  Rat   604 MSSFNGSHTLLENAADIGGVAIAFQAYRKRITERT-GELTLPNQELSPYQLFFRSYAQVMCRELI 667

  Fly   549 GALQQDR---KRQVTHATLRNSPEFLEAFRCRPGDVLYPQDQRC 589
            ....||.   .|...|..|.|||:|.:.|.|..|.:|.| ..||
  Rat   668 SQDPQDTHSPPRLRVHGPLSNSPDFAKHFLCPSGSLLNP-STRC 710

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nepl11	NP_649449.1	GluZincin	45..589	CDD:301352	143/689 (21%)
Kel	NP_001178540.1	PepO	75..713	CDD:226118	146/694 (21%)
		M13	78..711	CDD:189000	145/693 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3590
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	2	1.860