Protein Alignment Nepl11 and Phex

DIOPT Version :9

• Sequence 1: NP_649449.1
• Gene: Nepl11 / 40540
• FlyBaseID: FBgn0037230
• Length: 592
• Species: Drosophila melanogaster
• Sequence 2: NP_037136.2
• Gene: Phex / 25512
• RGDID: 3323
• Length: 749
• Species: Rattus norvegicus
• Alignment Length: 750
• Identity: 152/750 - (20%)
• Similarity: 264/750 - (35%)
• Gaps: 216/750 - (28%)

  Fly     5 ALAVLWIAGIAYGQDDLLRVETELLSF----SHNLEP-----------YLDTSKQPCQDFYGYVC 54
            ||| |:|.|.......|..|...||||    .:.|:|           .::.|..||::|:.:.|
  Rat    22 ALA-LFITGTLVLGTLLFLVSQGLLSFQAKQEYCLKPECIEAAAAIMSKVNLSVDPCENFFRFAC 85

  Fly    55 S----------------------HSANLSETGRQRFQSLLKETDVAQLMDME-LQLIN-FFKSCE 95
            .                      |:.:|      :.::|| |..|::..|.| :|... .:.||.
  Rat    86 DGWISNNPIPEDMPSYGVYPWLRHNVDL------KLKALL-EKSVSRRRDTEAVQKAKILYSSCM 143

  Fly    96 SGRGVEALKGSQL---YRQSG-GWPSLE----PNKVNASQRTNQTQRWLGLLGYFHEVGAPYFFE 152
            :.:.:|......|   .|.|. .||.||    |..|.:.::.:..|......|.:........:.
  Rat   144 NEKAIEKADAKPLLHILRHSPFRWPVLEANIGPEGVWSERKFSLLQTLATFRGQYSNSVFIRLYV 208

  Fly   153 TSVTMQSNKRLVVLQP------------DGTR-----RNTLRKFEQRVGEVLQSFGIEQSRAHVT 200
            :.....||:.::.|..            |.|.     |:.|.||......:|   |...|||...
  Rat   209 SPDDKASNEHILKLDQATLSLAVREDFLDNTTEAKSYRDALYKFMVDTAVLL---GANSSRAEHD 270

  Fly   201 ALEVLSLERSRRDI-VKADHVEDQVQFSYGNFKRIVFGNASLIRLDWDGYFRKLLGG------KT 258
            ...||.||....:| :..::...:..::..|...:   :|.:.:.||.||.:|::..      |.
  Rat   271 MKSVLRLEIKIAEIMIPHENRTSEAMYNKMNISEL---SAMIPQFDWLGYIKKVIDTRLYPHLKD 332

  Fly   259 PQASDTIVVKQLPRLVEYFALLQNTSMVRLLNW-IWTDYLMDIVDADCHQLSE--TYAGDLYAHV 320
            ...|:.:||:......:.|.:|.......:.|: :|.     :|.:....||.  .|....::.|
  Rat   333 IGPSENVVVRVPQYFKDLFRILGAERKKTIANYLVWR-----MVYSRIPNLSRRFQYRWLEFSRV 392

  Fly   321 VQRVT---------ANRVELA-------------------QMYSELGK----AYTDQL-GGSVWI 352
            :|..|         .|.:|.|                   :|..||.:    |:.|.| ..:.|:
  Rat   393 IQGTTTLLPQWDKCVNFIESALPYVVGKMFVNVHFQEDKKEMMEELIEGVRWAFIDMLEKENEWM 457

  Fly   353 D----EISRQSSRQFLGNIMHTT-LNGDERLDAAYHSILLGRRSLYRNLEKLRKFQRTRRLASHS 412
            |    ..:::.:|..|..:.:.. :..|..::....:|.......:.|:.:.||:     ||...
  Rat   458 DAGTKRKAQEKARAVLAKVGYPEFIMNDTYVNEDLKAIKFSESDYFGNVLQTRKY-----LAQSD 517

  Fly   413 AQQVRR---YAQMF---APVNAFLGQHNLST----------------------PLNY----LLLG 445
            ...:|:   ..:.|   ..||||   ::.||                      .|:|    :::|
  Rat   518 FFWLRKAVPKTEWFTNPTTVNAF---YSASTNQIRFPAGELQKPFFWGTEYPRSLSYGAIGVIVG 579

  Fly   446 EFFSRSLVAAGSSSRTQG---AWRSSDSERRFAIFQQCV-----------------GKQTNAIDL 490
            ..|:......|......|   .|.|.|||.:|....:|:                 ||:|
  Rat   580 HEFTHGFDNNGRKYDKNGNLDPWWSVDSEEKFKEKTKCMINQYSNYYWKKAGLNVKGKRT----- 639

  Fly   491 LLSLLAQ----RQALSAYGQWLATQAGLVERVDAVLAAGSSKMSLQRLFFVTSLLVDCRS----- 546
            |...:|.    |:|..||.:|:..:.   :.|:..|..|.: .:..:|||::...|.|.|
  Rat   640 LGENIADNGGLREAFRAYRKWINDRR---QGVEEPLLPGIT-FTNNQLFFLSYAHVRCNSYRPEA 700

  Fly   547 -----ELGALQQDRKRQVTHATLRNSPEFLEAFRC 576
                 ::||....:.|  .:..:.|..||.:||.|
  Rat   701 AREQVQIGAHSPPQFR--VNGAISNFEEFQKAFNC 733

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nepl11	NP_649449.1	GluZincin	45..589	CDD:301352	136/694 (20%)
Phex	NP_037136.2	M13	74..740	CDD:341056	136/696 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3590
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900