Protein Alignment Nepl11 and nep-25

DIOPT Version :9

• Sequence 1: NP_649449.1
• Gene: Nepl11 / 40540
• FlyBaseID: FBgn0037230
• Length: 592
• Species: Drosophila melanogaster
• Sequence 2: NP_495164.2
• Gene: nep-25 / 191543
• WormBaseID: WBGene00022874
• Length: 515
• Species: Caenorhabditis elegans
• Alignment Length: 597
• Identity: 105/597 - (17%)
• Similarity: 194/597 - (32%)
• Gaps: 191/597 - (31%)

  Fly    34 NLEPYLDTSKQPCQDFYGYVCSHSANLSETGRQRF----QSLLKETDVAQLMDMELQLINFFKSC 94
            :::.:.|.|..||.|||.:||....       :|:    .|.||...||:......: .:.||..
 Worm    31 HIKKHADFSVDPCVDFYAHVCPWKV-------ERYFMEDLSKLKAGMVAKYRKKHPK-FDKFKGE 87

  Fly    95 ESGRGVEALKGSQLYRQSGGWPSLEPNKVNASQRTNQTQRWLGLLGYFHEVGAPYFFETSVTMQS 159
            ::....||||...:.:...   ..:|:|...|.                      ||   ::.|.
 Worm    88 DAFAIAEALKQLNIEQLKS---ECKPSKPRLSS----------------------FF---ISAQD 124

  Fly   160 NKRLVVLQPDGTRRNTLRKFEQRVGEVL----QSFGIEQSRAHVTALEVLSLE---RSRRDIVKA 217
            |:.:                 :.|.|||    :::..|: :|.:...||..:|   .:|..:|.|
 Worm   125 NRTI-----------------ENVDEVLFPGFENYPCEE-KAAIIIKEVGEIEDYTTTRSVLVSA 171

  Fly   218 ----------DHVEDQVQFSYGNFKRIVFGNASLIRLDWDGYFRKLLGGKTPQASDTIVVKQLPR 272
                      :.::.:.:..:..||.::  :..:|:..|                    .|....
 Worm   172 VNGFITSKLVEKLDVKARKLFNKFKSVI--SKEIIKTPW--------------------AKNYKA 214

  Fly   273 LVEYFALLQNTSM-----VRLLNWIWTDYLMDIVDA---DCHQLSETYAGDLYAHVVQRVTANRV 329
            :.:|...|.|.:.     ||    |.....|::.::   ||.:..:.......|.:|.:..|.|.
 Worm   215 IEQYVEALSNITFRTFADVR----ITVKKSMELYESTEKDCRKKLDVAFSQPTAELVCKGVATRK 275

  Fly   330 ELAQMYSELGKAY-TDQLG--GSVWIDEISRQSSRQFLGNIMHTTLNGD-----------ERLDA 380
            ....:...:...: .||.|  ..|| ...:...:..::||.....||.|           ..:..
 Worm   276 AEELLDEPIEDIFPQDQAGILKDVW-QMFNSFDNSVYIGNEFLLLLNTDYFSDLYGSIGFSMIHE 339

  Fly   381 AYHSILLGRRSLYRNLEKLRKFQRTRRLASHSAQQVRRYAQMFAPVNAFLGQHNLSTPLNYLLLG 445
            ..|:::.....|.:.|.||     ..:.|.....|..:..:.|..|..   .||:....|..:..
 Worm   340 IMHTLVFDDNDLDKPLSKL-----WTKNADCVKDQALKTCETFPTVTE---MHNMKPACNTTVTF 396

  Fly   446 EFFSRSLVAAGSSSRTQGAWRSSDSERRFAIFQQCVGKQT-----NAIDLLLSLLAQRQALSAYG 505
            |..:..|.|      .:.|||         |::....::|     .|:|        ::.|..||
 Worm   397 EEDAADLAA------YRIAWR---------IYENSYARKTVVPNYEALD--------KKQLFFYG 438

  Fly   506 Q--WLATQAGLVERVDAVLAAGSSKMSLQRLFFVTSLLVDCRSELGALQQDRKRQVTHATLRNSP 568
            .  :...|.|:            |::..|.                 |......|..::.:....
 Worm   439 AAVFFCNQDGM------------SRVPFQN-----------------LAHSNNYQRVNSLMSQMK 474

  Fly   569 EFLEAFRCRPGD 580
            :|.:||:|:|.|
 Worm   475 QFSDAFKCKPTD 486

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nepl11	NP_649449.1	GluZincin	45..589	CDD:301352	103/586 (18%)
nep-25	NP_495164.2	Peptidase_M13	308..496	CDD:279739	42/239 (18%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3590
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900