Protein Alignment Nepl11 and nep-24

DIOPT Version :10

• Sequence 1: NP_649449.1
• Gene: Nepl11 / 40540
• FlyBaseID: FBgn0037230
• Length: 592
• Species: Drosophila melanogaster
• Sequence 2: NP_503005.3
• Gene: nep-24 / 190993
• WormBaseID: WBGene00013786
• Length: 567
• Species: Caenorhabditis elegans
• Alignment Length: 565
• Identity: 100/565 - (17%)
• Similarity: 185/565 - (32%)
• Gaps: 158/565 - (27%)

  Fly    29 LSFSHNLEPYLDTSKQPCQDFYGYVCSHSANLSETGRQRFQSLLKETDVAQLMDMELQLIN---- 89
            ::.:|.|..|.|.|..||.:|:.:.|         ||:.      |.:...:...:.:.||
 Worm    44 ITLAHMLHNYHDPSVDPCDNFHQFAC---------GREH------EHETEDIYTKKTKTINNIMK 93

  Fly    90 -FFKSCESGRGVEALKGSQLYR------------------------QS-GGWPSLEPNKVNASQR 128
             |.|..|:.|.........||:                        || |.||.::.....:...
 Worm    94 RFLKKNETSRSKSENAMRTLYKACKTLEKNSTASRNKALQDIFQDIQSIGAWPVVDDKWDESKFD 158

  Fly   129 TNQTQRWLGLLGYFHEVGAPYFFETSVTMQSNKRLVVLQPDGTRRNTLRKFEQRVGEVLQSFGIE 193
            .|.      .|.....:|...|....:....|.|...:.|:...|:.: ...:.:.|:|::..::
 Worm   159 LND------FLVNLVRLGRKNFGLFQMARYVNVRNFAIGPEAAWRHNV-DLGKTISEILKANSVQ 216

  Fly   194 QSRAHV--TALEVLSLERSRRDIVKADHVEDQVQFSY-----------GNFKRIVFGNASLIRLD 245
            .:...:  ...|.::||::     .:.|..:.||..|           .||.|:|
 Worm   217 TNNKKLLDDLAEYVNLEKA-----LSQHKFNTVQPGYIFSERSDFVSSVNFSRLV---------- 266

  Fly   246 WDGYFRKLLGGKTPQASDTIVVKQLPRLVEYF-------ALLQNTSMVRLLNWIWTDYLMDIVDA 303
                ...:...|.....:...:..|.....:|       .:::|||...|.|::    :...:|.
 Worm   267 ----LEMMSPDKRTLFPEVYQIMYLTNTSLFFGKNNNLETIIRNTSKRALANYL----IFKFIDT 323

  Fly   304 DCHQLSETYAGDLYAHVVQRVT--ANRVELAQMY------------SELGKAYTDQL----GGSV 350
            ....|  || |...|...|:|.  ..|..|...|            ::|.:|...||    |.:.
 Worm   324 SIADL--TY-GSPSAFCEQKVINFLPRAALRAFYRNFISKENRKKITKLTEATQVQLLKIIGATD 385

  Fly   351 WIDEISRQSSRQFLGNIMHTTLNGDE------RLDAAY-HSILLGRRSLYRNLEKLRKFQRTRRL 408
            |:...|::.:...:.: |:..:...:      :||..: |..|....:.|..:.|:.:|.|.:.:
 Worm   386 WMSIKSKKIAMDRVSS-MNMVIGYPDYFDPPGKLDGLFEHLNLSSSDTYYTVVRKINRFMREQEM 449

  Fly   409 ASHSAQQVRRY------------------AQMFAPV-------NAFLGQHNLSTPLNYLL--LGE 446
            ..::. :|..|                  ..:|||.       ::|....|::...|.|.  :|.
 Worm   450 DYYTG-EVPYYPLFPGLMTNAMYNANDNNLMIFAPFFDDPFFDSSFPDYANIAFTSNTLAHEMGH 513

  Fly   447 FFSRSL--VAAGSSSRTQGAWRSSDSERRFAIFQQCVGKQTNAID 489
            .||..|  :..|    |...|.:......:....:|:..|....|
 Worm   514 TFSPHLMDIMTG----TTEVWLTPKETEEYEKRVKCLEDQYTEYD 554

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nepl11	NP_649449.1	GluZincin	45..590	CDD:472708	95/549 (17%)
nep-24	NP_503005.3	GluZincin	58..561	CDD:472708	95/551 (17%)