Protein Alignment Nepl11 and nep-23

DIOPT Version :10

• Sequence 1: NP_649449.1
• Gene: Nepl11 / 40540
• FlyBaseID: FBgn0037230
• Length: 592
• Species: Drosophila melanogaster
• Sequence 2: NP_503004.2
• Gene: nep-23 / 178472
• WormBaseID: WBGene00013785
• Length: 714
• Species: Caenorhabditis elegans
• Alignment Length: 709
• Identity: 133/709 - (18%)
• Similarity: 231/709 - (32%)
• Gaps: 221/709 - (31%)

  Fly    27 ELLSFSHNLEPYLDTSKQPCQDFYGYVC--SHSANLSETGRQR----FQSLLKET----DVAQLM 81
            |.::.:|.|..|.|.|..||.:||..||  .|..:| ::|..:    .::|::||    .|....
 Worm    80 ECITLAHQLHNYHDPSADPCDNFYQSVCGKQHEHSL-KSGLAKKHLILRNLIRETITNRKVTPTS 143

  Fly    82 DMELQLINFFKSC--------ESGRGVEALKGSQLYR--QS-GGWPSLEPNKVNASQRTNQTQRW 135
            ..|.::..|...|        .|....:||:  .::|  || |.||:       .|:..|::.
 Worm   144 KSENEMRKFHGICSKYQRANSSSDIAQQALR--DIFRDVQSIGSWPA-------GSRNWNESD-- 197

  Fly   136 LGLLGYFHEVGAPYFFETSVTMQSNKRLVVLQPDGTRRNTLRKFEQRVGEVLQSFGIEQSRAHVT 200
                                 ...|:.|          |.|.|..||      :||:.|......
 Worm   198 ---------------------FNLNEML----------NNLVKLGQR------NFGLFQISFKYR 225

  Fly   201 ALEVLSLERSRRDIVKADH-----------VEDQVQFSYGNFKRIVFGNASLIRLDWDGYFRKLL 254
            ...::|.|..||:..|.:.           |.|::|     ..:.:.|.|||..|..:.|:...:
 Worm   226 DQLLISAEEHRRNYSKLEPTILNIFETNGLVPDRIQ-----LLKDLEGFASLEALLKNHYYLDNM 285

  Fly   255 GGKTPQASDTIVVKQLPRLVEYFALLQNTSMVRLLNWIWTDYLMDIVDADCHQLSETYAGD---- 315
            ....|...|.:|..     |::..|      |:.:.....::||..::.....|::|...|
 Worm   286 DKMKPAVLDDLVPS-----VDFMGL------VKAMISPGKEHLMPKIELKTSVLNQTLFNDENMN 339

  Fly   316 LYAHVV---QRVTANRVELAQMYSELGKAY---TDQLGGSV---WIDEISRQSSRQFLGN----- 366
            |.|.::   :|..||.:....:.|.|....   |.|.|.:.   .|..:.|.|.|.|:.|
 Worm   340 LEAIILDTPKRTLANYLIFNFIDSSLDHLVFETTSQKGNTCEDKVITYLPRASLRVFIRNYVDKE 404

  Fly   367 --------------IMHTTLNGDERLDAAYHSILLGR--------------------RSLYRNLE 397
                          .:||.:.....|.|....:.|.:                    ..:::||.
 Worm   405 NRDLITQLAEKTRIALHTLVQNSTWLKAESKQLALDKINAMGKMIGYPDFFEPPGTLDGMFKNLN 469

  Fly   398 ---------KLRKFQRTRRLASHSAQQVRRYAQMFAP---------VNAFL----GQHNLSTP-- 438
                     .|.|.:|      :..:|...|.....|         :||:.    .|.|...|
 Worm   470 LDSSDTYYTALNKLER------YFVEQKMDYFAEETPLDPDLRVFEMNAYYYIPGNQLNFLAPFF 528

  Fly   439 ------------LNYLLLGEFFSRSLVAAGS------SSRTQGAWRSSDSERRFAIFQQCVGKQT 485
                        :|..:.|......:..|..      :.|.:..|...:....:....||:..|.
 Worm   529 DDPMFDSTYPDYVNIAMSGNIIGHEMGHAFGPHAILRTVRGREVWMKPEELAEYESRAQCLANQY 593

  Fly   486 NAID------------LLLSLLAQRQALSAYGQWLATQAGLVERVDAVLAAGSSKMSLQRLFFVT 538
            :..|            ::..|:|..  :.....|...::  ::..:|....|.....:.:|:|..
 Worm   594 SEYDDPDFGRVFDGGKVIDELVADN--IGREVSWKMFKS--LDLTNATRIIGFEDYDIDQLYFRV 654

  Fly   539 SLLVDC-----RSELGALQQDRKRQV--THATLRNSPEFLEAFRCRPGDVLYPQDQRCN 590
            ..|..|     |...|:::....|:.  .:....|.|||..||.|..|..:.|: ::|:
 Worm   655 GALTHCTPHAMRDLKGSIESSHPRKAFRVNGVYANLPEFARAFNCPTGSPMNPR-KKCD 712

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nepl11	NP_649449.1	GluZincin	45..590	CDD:472708	126/689 (18%)
nep-23	NP_503004.2	M13	96..711	CDD:341056	126/690 (18%)