Protein Alignment Nepl11 and nep-26

DIOPT Version :9

• Sequence 1: NP_649449.1
• Gene: Nepl11 / 40540
• FlyBaseID: FBgn0037230
• Length: 592
• Species: Drosophila melanogaster
• Sequence 2: NP_001022540.1
• Gene: nep-26 / 174593
• WormBaseID: WBGene00014171
• Length: 807
• Species: Caenorhabditis elegans
• Alignment Length: 716
• Identity: 154/716 - (21%)
• Similarity: 268/716 - (37%)
• Gaps: 194/716 - (27%)

  Fly    39 LDTSKQPCQDFYGYVC----SHSANLS--------ETGR----QRFQSLLKETDVAQLMDM---E 84
            :|.|.:||.:||.:.|    :.|.||.        ||.|    |..|::.|..|.:..:..   |
 Worm   120 VDQSVEPCDNFYQFACGGWINQSVNLKYDSWNTLYETQRTAHDQIVQAMHKINDGSYPLPTNAGE 184

  Fly    85 LQLINFFKSCESGRGVEALKGSQLYR----QSGGW-PSL--------EPNKVNASQRTNQTQRW- 135
            ......::.|.....:|. .|..|:.    :.||| |.|        |..::...:...:.:|:
 Worm   185 RAAAKMYEQCMDTDTLEQ-TGLHLWERFVDELGGWMPELKNGALEQEESFEIELDEDEKKRRRFE 248

  Fly   136 ---LGLLGYFHEVGAPYFFETSVT-MQSNKRL--------VVLQPDGTRRN-------TLRKFE- 180
               :.|..:.:.|...::....|. :.|.:.|        ::|.|:....|       ...|.|
 Worm   249 IEDIILSAFNYSVFPLFWAGVEVNYLNSKEHLITIYEQLPILLAPEKYHYNKELTPEMIYGKMEG 313

  Fly   181 -------QRVGEVLQS-FGIEQSRAHVTALEVLSLERSRRDIVKADHVEDQVQFSYGNFKRIVFG 237
                   |:|||.|.: .|.:.:.           |:.|..|....::|.|:..:...|.:....
 Worm   314 PPVTRALQQVGEELSAVLGFDSTD-----------EKVRMMIANMIYLEYQITMAGSTFYKEKKE 367

  Fly   238 NASLIRL----------DWDGYFRKLLGGKTPQASDTIVVKQ-------LPRLVEYFALLQNTSM 285
            ..:::.|          :|. ||...|.|:....|:.|.:|.       |..:||  .|.|:.|.
 Worm   368 RYTVVMLRELQEIAPAINWH-YFLSRLVGENLSHSEPIALKTGTQWIPILSAIVE--KLKQSRSG 429

  Fly   286 VRLL-NWI-WTDYLMDIVDAD--CHQLSETYAGDLYA---------------------------- 318
            |.:| |:: |...:..:..|.  |.......|..||:
 Worm   430 VAVLKNYVKWKTIMFHLAYASPKCRDGLLWMAVSLYSGAASQRKEFCVLRLSGIFPLSLPSILRK 494

  Fly   319 -----HVVQRV-----TANRVELAQMYSELGKA---YTDQLGGSVWIDEISRQSSRQFLG--NIM 368
                 |..:.|     .|:|::  :.|.|:.::   ::|:......||:::..:  :|:|  :.|
 Worm   495 IDGIDHTEKNVKAVQNIADRIQ--EKYEEMVRSSNLFSDRETRENVIDKVNNMT--KFIGFPDAM 555

  Fly   369 HTTLNGDE---RL-DAAYHSILLGRRSLYR-NLEKL------RKFQRTRRLASHSAQQVRR---- 418
            .:....::   || |..:.|::||..|:|: .|::|      |.:..||...|..|....|
 Worm   556 RSDYEMEKEAVRLHDTLFWSMVLGSSSVYKERLQRLRLPVDPRSWVDTRPAISVPAHNYERNLVQ 620

  Fly   419 --YAQMFAPVNAFLGQHNLSTPLNYLLLGEFFSRSLVAA--------GSSSRTQGAWRSSDSERR 473
              :..:..|   :..:|.|.. .||..:|......|..|        |.:... |.|.|:||.|.
 Worm   621 IPFDSLRLP---YADEHQLDF-ANYAGIGTIIGHELTHAFDGQGKLHGPTGNL-GVWWSTDSIRE 680

  Fly   474 FAIFQQCVGKQTNAIDLLLSLLAQRQALSAYGQWLATQAGLVERVDAVLAAGS---------SKM 529
            |...:||..||...:.....:.|.::.|.   :.:|.|.||....:|..:.|:         .|.
 Worm   681 FKAREQCFVKQYAGLMDSHDMNAAKEGLY---ENIADQVGLKVAYEAWKSNGNQNSGRMPGLEKY 742

  Fly   530 SLQRLFFVTSLLVDC--RSELGALQ---QDRKRQVTHATLRNSPEFLEAFRCRPGDVLYPQDQRC 589
            |..:|||:......|  ||:...||   ::|.|.:  .:|:|||||..|::|.....:.|.| :|
 Worm   743 SQDQLFFLAYTQGWCALRSKSYKLQPHMEERIRML--GSLQNSPEFASAWKCSSESFMNPPD-KC 804

  Fly   590 N 590
            :
 Worm   805 S 805

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nepl11	NP_649449.1	GluZincin	45..589	CDD:301352	151/707 (21%)
nep-26	NP_001022540.1	PepO	111..807	CDD:226118	154/716 (22%)
		M13	124..805	CDD:189000	151/710 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910