Protein Alignment Nepl11 and nep-11

DIOPT Version :9

• Sequence 1: NP_649449.1
• Gene: Nepl11 / 40540
• FlyBaseID: FBgn0037230
• Length: 592
• Species: Drosophila melanogaster
• Sequence 2: NP_494538.1
• Gene: nep-11 / 173685
• WormBaseID: WBGene00017557
• Length: 848
• Species: Caenorhabditis elegans
• Alignment Length: 726
• Identity: 138/726 - (19%)
• Similarity: 252/726 - (34%)
• Gaps: 232/726 - (31%)

  Fly    39 LDTSKQPCQDFYGYVCSH----------------SANLSETGRQRFQSLLKETDVAQLMDMELQL 87
            ::||..||.||:.:.|..                .|...|..||:.:.||::..|.     |.:.
 Worm   177 MNTSVDPCDDFFEFACGQWNDQHPIPDDMYGFGTFAYAREQVRQQLRVLLEQEVVT-----ESES 236

  Fly    88 INF----FKSCESGRGVEALKGSQLYR---QSGGWPSLEPN----KVNASQRTNQTQRWLGLLGY 141
            ||.    ::||.:...::.|....|:.   :.|.||.|:.|    |.|.:.....::|
 Worm   237 INMARATYRSCMNKTQLDELMTGPLFETLTELGEWPLLQENWDKTKFNFTSLLVNSRR------- 294

  Fly   142 FHEVGAPYFFETSVTMQSNKRLVVLQPDGTRRNTL------------------------------ 176
              :.|...||:..:...|.         .|.||||
 Worm   295 --DYGVDVFFQLYIYADSK---------NTSRNTLFIDQSTLALGRGTRDYYLNTTLFSSHMTAY 348

  Fly   177 RKFEQRVGEVLQSFG-IEQSRAHVTA------------LEVLSLERSRRDIVKADHVEDQVQFSY 228
            ||:.:::..:|::.| :.:|.:.:.|            .:::..|..||:..:. :.:.|:|..|
 Worm   349 RKYLRQIAHLLKTDGNLTRSESEMNADIEKIIDFEIELAKIIVAEDERRNNTRL-YNKRQIQDLY 412

  Fly   229 GNFKRIVFGNASLIRLDWDGYFRKLLGGKTPQASD---------TIVVKQLPRLVEYFALLQNTS 284
            .          .|.::||..:|:.:      ..||         .|::.::..|.....|::.|.
 Worm   413 N----------LLPQVDWVPFFQSI------APSDLTHLFHNETEIIICEIEYLQHVSELIEKTD 461

  Fly   285 MVRLLNWI-W--------------TDYLMDIVDA------------DCHQLSETY----AGDLY- 317
            :..|.|:: |              .|...|.:..            ||.|:..|.    ||.:|
 Worm   462 VGLLTNYVLWRVVQSNVRYLDERFEDIKQDFLKVMTGQQQSPPRWKDCAQVPSTVLPLAAGAIYV 526

  Fly   318 -AHVVQRVTANRVELAQMYSELGKAYTDQLGGSVWIDE----ISRQSSRQFLGNIMHTTLNGD-E 376
             ||..:   :::.|..:|...|..::.|.:..:.|:||    ::.:.:...:.||.:..:..| .
 Worm   527 QAHFQE---SDKHEALRMIMHLRNSFADLVRQNDWMDEETKAVAIEKANSMINNIGYPDVTNDLP 588

  Fly   377 RLDAAYHSILLGRRSLYRNLEK-------LRKFQR-TRRLASHSAQQVRRYAQMFAPVNAFLGQH 433
            :||..|..:.:.....|..:.|       .|:||: |:....|      .:....|.||||....
 Worm   589 KLDKQYLGLSISDSDTYYYIMKKSVVWMQSREFQKLTKPFDKH------EFDISPAVVNAFYSPE 647

  Fly   434 N---------LSTP---------LNYLLLGEFFSRSLVAA----GSSSRTQG---AWRSSDSERR 473
            .         |..|         :||..:|......:...    ||.....|   .|.|..|...
 Worm   648 KNAITFPAGILQPPFFSGTFPKAVNYGAIGAVIGHEITHGFDDQGSQYDKDGNLHNWWSESSLNS 712

  Fly   474 FAIFQQCV-----------------GKQTNAIDLLLSLLAQRQALSAYGQWLATQAGLVERVDAV 521
            |...::|:                 ||.|.. :.:......::|..||.::: |:.|...|:
 Worm   713 FDTRRRCIVEQYGNYTVPKTNFRVNGKLTQG-ENIADNGGVKEAFQAYQKYV-TENGEEPRL--- 772

  Fly   522 LAAGSSKMSLQRLFFVTSLLVDC--RSELGALQQ----DRKRQVTH--ATLRNSPEFLEAFRCRP 578
              .|..:.:.:::|||:.....|  :.|..|:||    :...:|..  ..|.|...|.:.::| |
 Worm   773 --PGLQQYTNEQIFFVSYAHFWCGKKKEAAAMQQVLTDEHSPEVFRVIGVLSNMQAFADVYKC-P 834

  Fly   579 GDVLYPQDQRC 589
            .:.....|.:|
 Worm   835 RNAPVNPDHKC 845

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nepl11	NP_649449.1	GluZincin	45..589	CDD:301352	135/718 (19%)
nep-11	NP_494538.1	PepO	174..848	CDD:226118	138/726 (19%)
		M13	181..845	CDD:189000	135/720 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910