Protein Alignment Nepl11 and nep-9

DIOPT Version :9

• Sequence 1: NP_649449.1
• Gene: Nepl11 / 40540
• FlyBaseID: FBgn0037230
• Length: 592
• Species: Drosophila melanogaster
• Sequence 2: NP_494531.2
• Gene: nep-9 / 173683
• WormBaseID: WBGene00017554
• Length: 700
• Species: Caenorhabditis elegans
• Alignment Length: 686
• Identity: 141/686 - (20%)
• Similarity: 245/686 - (35%)
• Gaps: 177/686 - (25%)

  Fly    27 ELLSFSHNLEPYLDTSKQPCQDFYGYVCSHSANLSETGRQR-----------FQSLLKETDVAQL 80
            :.:..:..|:.|.||:.:.|:|||...|.:..:.....|.|           .:..|:..:....
 Worm    68 QCIILAQELKAYSDTATKSCEDFYKATCENYKDHQALDRHRDCKKRKAVNKLVRGFLQRDESTFT 132

  Fly    81 MDMELQLINFFKSC-ESGRGVEALKGSQLYRQSGGWPSLEPNKVNASQRTNQTQRWLGLLG---- 140
            .:.|..:...|..| |..|....|...:..::.|.||.||.|..::....:.....|..||
 Worm   133 SESESAIKLIFGKCDELSRNTSYLDIFKDIKKIGSWPVLEHNWKDSMFNLDDVIAKLVKLGSTDF 197

  Fly   141 --YFHEVGAPYFFETSVTMQSNKR----------LVVLQPDGTR----------------RNTLR 177
              :..|:....|...:|.:.|.:.          |.:|:.:|.:                :|.|:
 Worm   198 GLFKLELRKLAFGHFAVFVSSKQEQNIHQLEKTILGILKANGIQQDRKELSDDLKDYSDFKNHLK 262

  Fly   178 KFEQR---------VGEVLQSFGIE----QSRAHVTALEVLSLERSRRDIVKADHVEDQVQFSYG 229
            :|.|.         .|.::::.||.    |.....|.|:|.            :||.
 Worm   263 EFYQEETYIEYRLYAGSIVENLGISSLTTQMALKSTGLDVF------------NHVN-------- 307

  Fly   230 NFKRIVFGNASLIRLDWDGYF--RKLLGGKTPQASDTIVVKQLPRLVEYFALLQNTSMVRLLNWI 292
              :|.:..|:||       :|  ...||         :::::.|:     ..|.|..:...::.:
 Worm   308 --QRTLITNSSL-------FFGEENNLG---------MIIQKTPK-----RTLANFLIFHFIDVM 349

  Fly   293 WTDYLMDIVDADCHQLSETYAGDLYAHVVQRVTANRV------ELAQMYSELGKAYTDQLGGSVW 351
            .|| |.:...| |   .||....|....:|.::.|.|      ::.:|..:|....|:.:..|.:
 Worm   350 TTD-LANATKA-C---KETLIDLLPRASIQVLSRNFVNEDAQDDMVKMAQDLKTKITEMIDNSPF 409

  Fly   352 -------IDEISRQSSRQFLGNIMHTTLNGDERLDAAYHSI-LLGRRSLYRNLEKLRKFQRTRRL 408
                   .|...::...|.:..|...|....|.||..:..: |....|:||.::|||:. |:.:|
 Worm   410 FTKFHLVFDAEEQKKLIQKVKAIGIVTEYPQEVLDRDFERLNLTPSDSIYRTIQKLRRL-RSEQL 473

  Fly   409 ASH--------------SA--QQVRRYAQMFAPVNAFLGQHNLSTPLNYL-------LLGEFFSR 450
            ..|              ||  .|......:|||:  ..|.:..::..||:       :||....|
 Worm   474 IEHLGGDLDPTDTRVWGSAHYDQTTNNLTIFAPI--IDGPYFDTSYPNYVNQFLMGFILGRELGR 536

  Fly   451 SL----VAAGSSSRTQGAWRSSDSERRFAIFQQC-VGKQTNAIDLLLS-LLAQRQALSAYGQ--- 506
            ||    :......:|:. |...:|.:||....:| ..|...:.|.|.| ....||....|.|
 Worm   537 SLDSVRIRKDEKGQTEN-WLKPESLKRFDEHLKCWAEKYDKSADPLKSESKGIRQIEGRYIQNEM 600

  Fly   507 ----------WLATQAGLVERVDAVLAAGSSKMSLQRLFFVTSLLVDCRSELGALQ----QDRKR 557
                      |.|... |..:.:.||.. ...:.|:|:||....|..||...|:..    |:..:
 Worm   601 FADFIGHEASWRAFMK-LDVKNEEVLET-FKVIKLRRMFFNVQALYFCRPPSGSTDWLSYQEHHQ 663

  Fly   558 QVT---HATLRNSPEFLEAFRCRPGDVLYPQDQRCN 590
            ..:   :...:|.|:|..||.|...|.:.||: :|:
 Worm   664 HYSFRVNGAFKNMPQFALAFECASDDDMNPQN-KCS 698

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nepl11	NP_649449.1	GluZincin	45..589	CDD:301352	136/665 (20%)
nep-9	NP_494531.2	M13	87..698	CDD:189000	136/665 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3590
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810