Protein Alignment Nepl11 and nep-13

DIOPT Version :10

• Sequence 1: NP_649449.1
• Gene: Nepl11 / 40540
• FlyBaseID: FBgn0037230
• Length: 592
• Species: Drosophila melanogaster
• Sequence 2: NP_001342017.1
• Gene: nep-13 / 173672
• WormBaseID: WBGene00018196
• Length: 732
• Species: Caenorhabditis elegans
• Alignment Length: 697
• Identity: 140/697 - (20%)
• Similarity: 252/697 - (36%)
• Gaps: 187/697 - (26%)

  Fly    27 ELLSFSHNLEPYLDTSKQPCQDFYGYVC----SHS------ANLSETGRQRF--QSLLKETDVAQ 79
            |.::.|..|..:.:|:..||:|||.|.|    .|:      ||..:|...:.  |.:||......
 Worm    88 ECITLSSTLLNWQNTNIDPCEDFYEYSCGRYQEHTLNDGIRANEKDTIVMKLIRQFVLKNQSTTS 152

  Fly    80 LMDMELQLINFFKSC-------ESGRGVEALKGS--QLYRQSGGWPSLEPNKVNASQRTNQTQRW 135
            ..:..|.|:  ::.|       ...:..|.::..  :..|:.|.||..:.|..::....|   ..
 Worm   153 NSENALMLL--YEKCSLRYRMENRHQETEVIQREVFENIRKIGSWPIADKNWNSSHFNLN---NM 212

  Fly   136 LGLLGYFHEVGAPY-FFETSV----TMQSNKRLVVLQP-----------------DGTRRNTLRK 178
            |..:...|.:  |: .|||.|    .|.:..:.:|::|                 |....|.:..
 Worm   213 LSNMASIHML--PFGLFETRVIELYPMNTTAKQLVIRPTKLKFSIPQEELVRAIRDLLSVNGITS 275

  Fly   179 FEQRVGE-VLQSFGIEQSRAHV------TALEVLSLERSRRDIVKADHVEDQVQFSYGNFKRIV- 235
            ..::|.| |.:||.:::...::      ....:..|:::..||               :|:||:
 Worm   276 IMKKVKEDVAESFALDKEIGNIHIDPQPKPATLSELQKAVPDI---------------DFERIIK 325

  Fly   236 ------FGNASLIRLDWDGYFRKLLGGKTPQASDTIVVKQLPRLV-----------EYFALLQNT 283
                  .||.|.:|........:|..||....| :|:.:..||::           .||....||
 Worm   326 SYLNPKTGNWSSLRTKIFSARFELFFGKNNNLS-SIIARTKPRILANYLFLKYIEYAYFFFFDNT 389

  Fly   284 SMVRLLNWIWTDYLMDIVDADCHQLSETYAGDLYAHVVQRVTANRVELAQMYSELGK-AYTDQLG 347
            .:     :...|:..::|.....:.|      |...|........:.:|....|:.| ||.:.:.
 Worm   390 KV-----FSDDDFCTEVVTTSLPRAS------LRVFVRNHFKKENMAVASEIVEVVKTAYVEIIN 443

  Fly   348 GSVWIDEISRQSS-------RQFLGNIMHTTLNGDERLDAAYHSILLGRR-SLYRNLEKLRKFQR 404
            .|.|:...:|:|:       ::.:|........|  .||..:.::.|.|. |.:..:.|:.:|:.
 Worm   444 NSTWLHNSTRESAIEKVVKMKKVIGYTEEYERTG--ALDEMFETLQLSRSDSFFVLMTKVNRFKI 506

  Fly   405 TRRLASHSAQQVRRYAQMFAPVNAF-LGQHNLSTPLNYLL------LGEF-FSRSLVAAG----- 456
            .:.:...|:..:....:.....||| ....||   ||.|:      |.:| :.|.:..||
 Worm   507 EQLMDFVSSDSLLNPIEPLVMANAFYFPTKNL---LNVLVPFLDKPLFDFKYPRYVAMAGVGRVL 568

  Fly   457 ----------------SSSRTQGAWRSSDSE---RRFAIFQQ---------CVGKQTNAIDLLLS 493
                            ...||:..|...|:|   ||...|.:         ..||| |..::|..
 Worm   569 AHEIGHAFDINGRQTDEIGRTRDWWTREDTEEYDRRSECFAEQFTNFKDPSFKGKQ-NGTEVLAE 632

  Fly   494 LLAQRQALSAYGQWLA-------TQAGLVERVDAVLAAGSSKMSLQRLFFVTSLLVDCRSELGAL 551
            ::|  .||.....|:|       .:.||::..|         ....:|:|..:.|..|..  ..:
 Worm   633 IIA--DALGMEASWIAFKKINLTEEQGLIQFED---------HDFGKLYFQVAALDFCAP--SRI 684

  Fly   552 QQDRKRQVTHAT--------LRNSPEFLEAFRCRPGDVLYPQDQRCN 590
            ::....|::|.|        ..||..|.:.::|..|..:.|. |||:
 Worm   685 EERYSDQLSHPTNKFRINGAFSNSRAFADTYKCPVGSKMNPV-QRCD 730

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nepl11	NP_649449.1	GluZincin	45..590	CDD:472708	135/677 (20%)
nep-13	NP_001342017.1	M13	104..729	CDD:341056	134/678 (20%)