DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG9766 and Potea

DIOPT Version :9

Sequence 1:	NP_001097672.1	Gene:	CG9766 / 40539	FlyBaseID:	FBgn0037229	Length:	340	Species:	Drosophila melanogaster
Sequence 2:	NP_001365522.1	Gene:	Potea / 67575	MGIID:	1914825	Length:	2320	Species:	Mus musculus

Alignment Length:	278	Identity:	63/278 - (22%)
Similarity:	108/278 - (38%)	Gaps:	67/278 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    94 IKALTVSKDGHCYVPLAISPEIVACTAAALPSTHCLSRAIRKGQQFLVKRMLRRRPSLMEYPASN 158
            :|:::|..:.. |.||....:     ||:...|..|.|.|..|:..:..|..:.|.:
Mouse    32 MKSISVPNEPR-YKPLRKIHQ-----AASDGDTERLQRMISLGKHSVHDRDFKERTA-------- 82

  Fly   159 GFLPLANAIIQGEMCIIDLLLSAGCSV----------------------------HIGDPG---- 191
                |..|...|::.::.:||...|.:                            |..||.
Mouse    83 ----LHFACACGQVEVVSILLRNNCDIDAADMNFITPLMKAVQNWTYECVCILLKHGADPNRKDK 143

  Fly   192 SGRTPLHLAFYYGHLPSARILLNKKARLEATDSNGMTPAHCAVDANQLEIVKFALEAGANAEARD 256
            :|.|.||.|....:...|:.||...|.:|..:.:|.||...|:..|::|:.||.::.|||....|
Mouse   144 NGNTSLHYAVSEDNQTLAKCLLKYSANMEQKNKDGFTPLLLALKENKIEMAKFLVKMGANIHVFD 208

  Fly   257 VCGWTLLMRAVVMNASMELIKVLVTHGADL------------AALDGVGKTCTDLAKLYH---RQ 306
            ......|:.|:..: |.:::.:|:..|.|.            .|::|..|...::...|.   |:
Mouse   209 DMRRNTLLYAIRWD-SKDMVNLLLDEGIDFFFRDVFGWTALRYAIEGTSKGSREILMNYDEMLRR 272

  Fly   307 EAKDYFDEVQKFRLEKSV 324
            :.||...| .||..:||:
Mouse   273 KNKDGIPE-YKFFEDKSL 289

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9766	NP_001097672.1	FN3	35..98	CDD:214495	1/3 (33%)
		ANK	128..244	CDD:238125	31/147 (21%)
		ANK repeat	128..156	CDD:293786	6/27 (22%)
		Ank_2	129..223	CDD:289560	25/125 (20%)
		ANK repeat	158..189	CDD:293786	7/58 (12%)
		ANK repeat	192..223	CDD:293786	10/30 (33%)
		ANK	193..311	CDD:238125	34/132 (26%)
		Ank_2	197..290	CDD:289560	27/104 (26%)
		ANK repeat	225..256	CDD:293786	11/30 (37%)
		ANK repeat	258..290	CDD:293786	7/43 (16%)
Potea	NP_001365522.1	ANK repeat	49..76	CDD:293786	7/31 (23%)
		Ank_2	65..>252	CDD:423045	41/199 (21%)
		ANK repeat	80..109	CDD:293786	7/40 (18%)
		ANK repeat	114..142	CDD:293786	3/27 (11%)
		ANK repeat	144..175	CDD:293786	10/30 (33%)
		ANK repeat	177..208	CDD:293786	11/30 (37%)
		ANK repeat	210..235	CDD:293786	4/25 (16%)
		Smc	<1772..1994	CDD:224117
		DUF3496	1956..2060	CDD:403277
		DUF3496	2181..2284	CDD:403277
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1514637at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010