DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG9766 and ANKRD23

DIOPT Version :9

Sequence 1:	NP_001097672.1	Gene:	CG9766 / 40539	FlyBaseID:	FBgn0037229	Length:	340	Species:	Drosophila melanogaster
Sequence 2:	NP_659431.5	Gene:	ANKRD23 / 200539	HGNCID:	24470	Length:	305	Species:	Homo sapiens

Alignment Length:	185	Identity:	55/185 - (29%)
Similarity:	90/185 - (48%)	Gaps:	23/185 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly   131 RAIRKGQQFLVKRMLRRRPSLMEYPASNGFLPLAN----------AIIQGEMCIIDLLLSAGCSV 185
            :|..:.|::|:.:.|           ::|..|.|:          |.::|...:::.||.||.:|
Human   117 KAAAENQEYLIDKYL-----------TDGGDPNAHDKLHRTALHWACLKGHSQLVNKLLVAGATV 170

  Fly   186 HIGDPGSGRTPLHLAFYYGHLPSARILLNKKARLEATDSNGMTPAHCAVDANQLEIVKFALEAGA 250
            ...|. ..|||:..|...|||...:.|||:.||:.|.|..|.||.|.||.....:.::..:|.||
Human   171 DARDL-LDRTPVFWACRGGHLVILKQLLNQGARVNARDKIGSTPLHVAVRTRHPDCLEHLIECGA 234

  Fly   251 NAEARDVCGWTLLMRAVVMNASMELIKVLVTHGADLAALDGVGKTCTDLAKLYHR 305
            :..|:|..|.|.|..| |.:.|.:.:|:|:.:||:|...:....|...||:.:.|
Human   235 HLNAQDKEGDTALHEA-VRHGSYKAMKLLLLYGAELGVRNAASVTPVQLARDWQR 288

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9766	NP_001097672.1	FN3	35..98	CDD:214495
		ANK	128..244	CDD:238125	35/122 (29%)
		ANK repeat	128..156	CDD:293786	4/24 (17%)
		Ank_2	129..223	CDD:289560	28/101 (28%)
		ANK repeat	158..189	CDD:293786	10/40 (25%)
		ANK repeat	192..223	CDD:293786	13/30 (43%)
		ANK	193..311	CDD:238125	40/113 (35%)
		Ank_2	197..290	CDD:289560	33/92 (36%)
		ANK repeat	225..256	CDD:293786	10/30 (33%)
		ANK repeat	258..290	CDD:293786	11/31 (35%)
ANKRD23	NP_659431.5	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	83..104
		ANK	138..263	CDD:238125	41/126 (33%)
		ANK 1	143..172		7/28 (25%)
		ANK repeat	145..174	CDD:293786	7/28 (25%)
		ANK 2	176..205		12/28 (43%)
		ANK repeat	178..207	CDD:293786	13/28 (46%)
		Interaction with TTN. /evidence=ECO:0000269\|PubMed:14583192	178..195		7/16 (44%)
		ANK repeat	209..240	CDD:293786	10/30 (33%)
		ANK 3	209..238		9/28 (32%)
		PHA02917	<225..>303	CDD:332678	20/65 (31%)
		ANK repeat	242..273	CDD:293786	11/31 (35%)
		ANK 4	242..271		11/29 (38%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1514637at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	1.010