DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG9766 and fank1

DIOPT Version :9

Sequence 1:	NP_001097672.1	Gene:	CG9766 / 40539	FlyBaseID:	FBgn0037229	Length:	340	Species:	Drosophila melanogaster
Sequence 2:	XP_017951317.1	Gene:	fank1 / 100495570	XenbaseID:	XB-GENE-6084370	Length:	345	Species:	Xenopus tropicalis

Alignment Length:	300	Identity:	84/300 - (28%)
Similarity:	144/300 - (48%)	Gaps:	29/300 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    23 EEYKLLWPD--FVSRISNPTVNSVQLHWSL---LKNAS------VYCID----KFHKRLGWLQLD 72
            ::..:|.||  .:.::|:   :|::|:|.:   ||..|      .:.|:    |.|. .|.:...
Frog    14 DQNTILKPDPPVIGKVSH---HSIELYWDINNNLKQKSSSNKWIKFTIEEEDIKTHV-FGTIYSG 74

  Fly    73 WTSSSPITVTNLEENFGYRLRIKALTVSKDGHCYVPLAISPEIVACTAAALPSTHCLSRAIRKGQ 137
            :  |...||..||.:..||.|:|....:.| :.|.|:.    .|:.|...|...| |.||:....
Frog    75 Y--SRRHTVEGLEPSSPYRFRLKVTGYNGD-YAYSPVV----SVSTTREPLSGQH-LHRAVNMND 131

  Fly   138 QFLVKRMLRRRPSLMEYPASNGFLPLANAIIQGEMCIIDLLLSAGCSVHIGDPGSGRTPLHLAFY 202
            :..||.:|......::.|...||.||..|..:|.:.:::||...|..::..: |||:..|.||.:
Frog   132 EHEVKNILETGHVKVDIPDKLGFTPLMVAAQKGFLRLVELLTEHGADINQMN-GSGKNSLMLACF 195

  Fly   203 YGHLPSARILLNKKARLEATDSNGMTPAHCAVDANQLEIVKFALEAGANAEARDV-CGWTLLMRA 266
            .|||...:.|..:.|..|:.|..|.|..|.|.|...|::|::.::.|...::||. ..||.|||.
Frog   196 AGHLNIVQYLRGQGASWESRDKAGCTAMHWAADGGHLKVVQWMIDDGCKIDSRDSHLEWTPLMRI 260

  Fly   267 VVMNASMELIKVLVTHGADLAALDGVGKTCTDLAKLYHRQ 306
            ..::.::::.:.|:..||.:.|.|..|||...:|.|.:.:
Frog   261 AAVSGNVDIARCLIAAGAGVNAKDTNGKTPLMVAVLNNHE 300

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9766	NP_001097672.1	FN3	35..98	CDD:214495	20/75 (27%)
		ANK	128..244	CDD:238125	36/115 (31%)
		ANK repeat	128..156	CDD:293786	6/27 (22%)
		Ank_2	129..223	CDD:289560	28/93 (30%)
		ANK repeat	158..189	CDD:293786	9/30 (30%)
		ANK repeat	192..223	CDD:293786	11/30 (37%)
		ANK	193..311	CDD:238125	36/114 (32%)
		Ank_2	197..290	CDD:289560	29/93 (31%)
		ANK repeat	225..256	CDD:293786	8/30 (27%)
		ANK repeat	258..290	CDD:293786	9/31 (29%)
fank1	XP_017951317.1	FN3	21..113	CDD:238020	26/102 (25%)
		Ank_4	122..172	CDD:372654	14/50 (28%)
		ANK repeat	123..150	CDD:293786	6/26 (23%)
		ANK repeat	153..183	CDD:293786	9/29 (31%)
		Ank_2	157..249	CDD:372319	27/92 (29%)
		ANK repeat	185..216	CDD:293786	11/30 (37%)
		ANK repeat	219..249	CDD:293786	8/29 (28%)
		Ank_2	223..317	CDD:372319	23/77 (30%)
		ANK repeat	252..284	CDD:293786	9/31 (29%)
		ANK repeat	286..317	CDD:293786	5/14 (36%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1514637at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010