DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG9766 and ppp1r27a

DIOPT Version :9

Sequence 1:	NP_001097672.1	Gene:	CG9766 / 40539	FlyBaseID:	FBgn0037229	Length:	340	Species:	Drosophila melanogaster
Sequence 2:	XP_002661302.2	Gene:	ppp1r27a / 100332066	ZFINID:	ZDB-GENE-131121-348	Length:	226	Species:	Danio rerio

Alignment Length:	238	Identity:	58/238 - (24%)
Similarity:	99/238 - (41%)	Gaps:	27/238 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    24 EYKLLWPDFVSRISNPTVNS----VQLHWSLLK-NASVYCIDKF-----HKRLGWLQLDWTSSSP 78
            :|...:|  ||:.:.|...|    ...|:|... :.|.|...|:     |.|..:....:|.:..
Zfish     2 KYSYQYP--VSQYTRPHYTSSTQYTPSHYSSSSYSPSYYSSSKYSPTTLHTRKYYTPPAYTPAYK 64

  Fly    79 ITVTNLEENFGYRLRIKALTVSKDGHCYVPLAISPEIVACTAAALPSTH--CLSRAIRKGQQFLV 141
            .|.|:          :.:.|..........:.|:|.:....|.|:..|:  .....:|..:...:
Zfish    65 PTYTS----------VCSKTSRPSSSPRTAVQITPSVTLKPARAVRFTNDVVFQDLVRHSELEQI 119

  Fly   142 KRMLRRRPSLMEYPASNGFLPLANAIIQGEMCIIDLLLSAGCSVHIGDPGSGRTPLHLAFYYGHL 206
            .|.:|.|...::....:|...|..|::.|.:..:.||:..|..||..|. :|.||||:|...|:.
Zfish   120 GRFMRARKVRLDTIFHSGMAALHEAVLSGSLECVKLLIKYGADVHQRDE-NGWTPLHMACSDGYP 183

  Fly   207 PSARILLNKKARLEATDSNGMTPAHCAVDANQLEIVKFALEAG 249
            ..|:.||:..|.:||.:.||..||. .:|.:..|::|. .|.|
Zfish   184 EIAKYLLSLGASVEAENENGEKPAD-LIDPDCKELLKL-FETG 224

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9766	NP_001097672.1	FN3	35..98	CDD:214495	12/72 (17%)
		ANK	128..244	CDD:238125	33/115 (29%)
		ANK repeat	128..156	CDD:293786	4/27 (15%)
		Ank_2	129..223	CDD:289560	27/93 (29%)
		ANK repeat	158..189	CDD:293786	9/30 (30%)
		ANK repeat	192..223	CDD:293786	13/30 (43%)
		ANK	193..311	CDD:238125	22/57 (39%)
		Ank_2	197..290	CDD:289560	19/53 (36%)
		ANK repeat	225..256	CDD:293786	9/25 (36%)
		ANK repeat	258..290	CDD:293786
ppp1r27a	XP_002661302.2	ANK	<135..218	CDD:238125	29/84 (35%)
		ANK repeat	136..167	CDD:293786	9/30 (30%)
		Ank_4	137..190	CDD:290365	18/53 (34%)
		ANK repeat	169..200	CDD:293786	13/30 (43%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1514637at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	1.010