DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG9766 and ankrd2

DIOPT Version :9

Sequence 1:	NP_001097672.1	Gene:	CG9766 / 40539	FlyBaseID:	FBgn0037229	Length:	340	Species:	Drosophila melanogaster
Sequence 2:	NP_001090801.1	Gene:	ankrd2 / 100037897	XenbaseID:	XB-GENE-1016694	Length:	310	Species:	Xenopus tropicalis

Alignment Length:	325	Identity:	81/325 - (24%)
Similarity:	138/325 - (42%)	Gaps:	65/325 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 LENKSNQSEDELDDKLTQEEYKLLWPDFVSRISNPTVNSVQLHWS---LLKN-ASVYCIDKFHKR 65
            :|::...:.|.:|.||..||::.:.|.| .:|....::|..|:..   |.:| |::...|:..|.
Frog     1 MEDEVKWATDIIDQKLELEEHEKVKPRF-RKIGVVDIDSSDLNDGKPPLNRNLANLKGDDRVRKT 64

  Fly    66 ----------LGWLQLDWTSSSPITVTNLEENFGYRLRIKALTVSKDGHCYVPLAISPEIVACTA 120
                      :|.:|         .:..:.:....|.:.|:|||:.:    .|....|.....||
Frog    65 SVDLRKEIIDVGGIQ---------NLIEIRKKRQERKKKKSLTVAPE----PPPEPEPLTGPVTA 116

  Fly   121 AALPSTHCLSRAIRKGQQFLVKRMLR-----------RRPSLMEYPASNGFLPLANAIIQGEMCI 174
            .|.     |..|: :|:..::::.|.           ||.:            |..|.::|.:.|
Frog   117 EAF-----LKAAV-EGKMNIIEKFLEDGGSPDTCDEFRRTA------------LHRASLEGHIEI 163

  Fly   175 IDLLLSAGCSVHIGDPGSGR---TPLHLAFYYGHLPSARILLNKKARLEATDSNGMTPAHCAVDA 236
            |..||.:|.||:..|    |   |.:|.|...|.|...::|.:..|.:...|....||.|.|...
Frog   164 IKKLLDSGSSVNFRD----RLDCTAIHWACRGGKLEIVKLLQDSGAEINVKDKLLSTPLHVATRT 224

  Fly   237 NQLEIVKFALEAGANAEARDVCGWTLLMRAVVMNASMELIKVLVTHGADLAALDGVGKTCTDLAK 301
            ....||:..:..|....|||..|.|.|..:|.:| ..::||:|:.:|:::.|.:..|||.|||.:
Frog   225 GHAHIVEHLIATGVEINARDREGDTALHDSVRLN-RYKIIKMLILYGSNMMAKNAEGKTPTDLVQ 288

Fly 302 301
Frog 289 288

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9766	NP_001097672.1	FN3	35..98	CDD:214495	12/76 (16%)
		ANK	128..244	CDD:238125	32/129 (25%)
		ANK repeat	128..156	CDD:293786	6/38 (16%)
		Ank_2	129..223	CDD:289560	25/107 (23%)
		ANK repeat	158..189	CDD:293786	10/30 (33%)
		ANK repeat	192..223	CDD:293786	8/33 (24%)
		ANK	193..311	CDD:238125	35/112 (31%)
		Ank_2	197..290	CDD:289560	27/92 (29%)
		ANK repeat	225..256	CDD:293786	8/30 (27%)
		ANK repeat	258..290	CDD:293786	10/31 (32%)
ankrd2	NP_001090801.1	ANK repeat	118..145	CDD:293786	5/32 (16%)
		ANK	142..267	CDD:238125	39/141 (28%)
		ANK repeat	149..178	CDD:293786	11/40 (28%)
		ANK repeat	180..211	CDD:293786	7/30 (23%)
		ANK repeat	213..244	CDD:293786	8/30 (27%)
		ANK repeat	246..277	CDD:293786	10/31 (32%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1514637at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010