DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG9766 and fank1

DIOPT Version :9

Sequence 1:	NP_001097672.1	Gene:	CG9766 / 40539	FlyBaseID:	FBgn0037229	Length:	340	Species:	Drosophila melanogaster
Sequence 2:	XP_002664080.5	Gene:	fank1 / 100005699	ZFINID:	ZDB-GENE-130613-3	Length:	378	Species:	Danio rerio

Alignment Length:	273	Identity:	69/273 - (25%)
Similarity:	120/273 - (43%)	Gaps:	20/273 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly    33 VSRISNPTVNSVQLHWSLLK---------NASVYCIDKFHK-RLGWLQLDWTSSSPITVTNLEEN 87
            |.::|:   :|::|.||..|         |.:.:.:::.:. :..:.|:....::..||.|||..
Zfish    57 VGQVSH---HSIELVWSREKGSKWTDPPQNWTCFILEQMNNTKHSFKQIHKGYNTRFTVDNLEPK 118

  Fly    88 FGYRLRIKALTVSKDGHCYVPLAISPEIVACTAAALPSTHCLSRAIRKGQQFLVKRMLRRRPSLM 152
            ..|..|:|....|.....|      |.:.|.|.....:...|..|:.|..:..:.|:|:.....:
Zfish   119 TTYTFRLKVTWPSGQQQYY------PSVTASTEKPPLNGKNLHSAVLKTDEVELCRVLQSGTVTV 177

  Fly   153 EYPASNGFLPLANAIIQGEMCIIDLLLSAGCSVHIGDPGSGRTPLHLAFYYGHLPSARILLNKKA 217
            :.|....:.||..|.|:|....:.:|:..|..|...: .||:..|.||.::|||...::|....|
Zfish   178 DVPDRLDYTPLMMAAIKGFTSGVQILVHHGADVSRKN-SSGKDSLMLACFHGHLDVVKLLCGCGA 241

  Fly   218 RLEATDSNGMTPAHCAVDANQLEIVKFALEAGANAEARDVCGWTLLMRAVVMNASMELIKVLVTH 282
            ...|.|..|....|.|....||:|:::.::.|.....:|...||.||...|:.....:..:|::.
Zfish   242 SWRARDRTGCCSLHWATAGGQLDILQYLIQYGCEVNVQDNIAWTPLMIVSVITGDPAVASLLISA 306

  Fly   283 GADLAALDGVGKT 295
            |||:...|..|||
Zfish   307 GADVNVQDRDGKT 319

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9766	NP_001097672.1	FN3	35..98	CDD:214495	16/72 (22%)
		ANK	128..244	CDD:238125	32/115 (28%)
		ANK repeat	128..156	CDD:293786	5/27 (19%)
		Ank_2	129..223	CDD:289560	25/93 (27%)
		ANK repeat	158..189	CDD:293786	8/30 (27%)
		ANK repeat	192..223	CDD:293786	11/30 (37%)
		ANK	193..311	CDD:238125	32/103 (31%)
		Ank_2	197..290	CDD:289560	27/92 (29%)
		ANK repeat	225..256	CDD:293786	7/30 (23%)
		ANK repeat	258..290	CDD:293786	9/31 (29%)
fank1	XP_002664080.5	FN3	53..144	CDD:238020	21/95 (22%)
		ANK	154..270	CDD:238125	32/116 (28%)
		ANK repeat	154..181	CDD:293786	5/26 (19%)
		ANK repeat	186..214	CDD:293786	8/27 (30%)
		ANK	213..337	CDD:238125	33/108 (31%)
		ANK repeat	216..247	CDD:293786	11/30 (37%)
		ANK repeat	254..280	CDD:293786	6/25 (24%)
		ANK repeat	282..314	CDD:293786	9/31 (29%)
		ANK	311..>369	CDD:238125	4/9 (44%)
		ANK repeat	316..347	CDD:293786	3/4 (75%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E33208_3BKQB
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG50214
OrthoDB	1	1.010	-	-		D1514637at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	3.830