Protein Alignment CG14644 and PHB

DIOPT Version :9

• Sequence 1: NP_649445.3
• Gene: CG14644 / 40536
• FlyBaseID: FBgn0250821
• Length: 293
• Species: Drosophila melanogaster
• Sequence 2: NP_001268425.1
• Gene: PHB / 5245
• HGNCID: 8912
• Length: 272
• Species: Homo sapiens
• Alignment Length: 221
• Identity: 50/221 - (22%)
• Similarity: 99/221 - (44%)
• Gaps: 49/221 - (22%)

  Fly    90 GPGVIFLVPCIDDLAVVDIRTRSFDLHRQEILT--RDMVTISID-GVVYYSIKSP----FDAMLQ 147
            |.|..||:|.:....:.|.|:|..::   .::|  :|:..::|. .:::..:.|.    |.::.:
Human    51 GEGTHFLIPWVQKPIIFDCRSRPRNV---PVITGSKDLQNVNITLRILFRPVASQLPRIFTSIGE 112

  Fly   148 VYD----PEEATEKLAMTTLRNVAGTHKLMDLLSSKEYLSNQIEGILYNSTEPWGIRV------- 201
            .||    |...||.|.....|..||     :|::.:|.:|.|:...|......:|:.:
Human   113 DYDERVLPSITTEILKSVVARFDAG-----ELITQRELVSRQVSDDLTERAATFGLILDDVSLTH 172

  Fly   202 --------ERVEIKEIFMPDQLKRALAVEQEAMREAKAKVAAAQGERDAVTALKEAADIMETNPI 258
                    |.||.|:: ...:.:||..|.::|.::.||.:.:|:|:       .:||::: .|.:
Human   173 LTFGKEFTEAVEAKQV-AQQEAERARFVVEKAEQQKKAAIISAEGD-------SKAAELI-ANSL 228

  Fly   259 A------LQLRYLQTLNSICNDDTRS 278
            |      ::||.|:....|....:||
Human   229 ATAGDGLIELRKLEAAEDIAYQLSRS 254

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG14644	NP_649445.3	PHB	64..223	CDD:214581	35/158 (22%)
		SPFH_like	89..292	CDD:302763	50/221 (23%)
PHB	NP_001268425.1	SPFH_prohibitin	27..221	CDD:259799	40/185 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0330
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810