DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG14644 and Stoml2

DIOPT Version :9

Sequence 1:	NP_649445.3	Gene:	CG14644 / 40536	FlyBaseID:	FBgn0250821	Length:	293	Species:	Drosophila melanogaster
Sequence 2:	NP_001026816.1	Gene:	Stoml2 / 298203	RGDID:	1308285	Length:	353	Species:	Rattus norvegicus

Alignment Length:	236	Identity:	70/236 - (29%)
Similarity:	118/236 - (50%)	Gaps:	25/236 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    24 SLLPQRNVKTSENVPPTCAEKTLFVLSMILIVLCLPWSLFCCLRVMSEYERAVILRLGRLRPKPP 88
            :||.:.:|:.|..:|...:..    |....::|.:|           :.|..|:.|:||..
  Rat    11 ALLLRGSVQASGRIPRRASSG----LPRNTVILFVP-----------QQEAWVVERMGRFH---- 56

  Fly    89 R--GPGVIFLVPCIDDLAVV-DIRTRSFDLHRQEILTRDMVTISIDGVVYYSIKSPFDAMLQVYD 150
            |  .||:..|:|.:|.:..| .::....::..|..:|.|.||:.||||:|..|..|:.|...|.|
  Rat    57 RILEPGLNVLIPVLDRIRYVQSLKEIVINVPEQSAVTLDNVTLQIDGVLYLRIMDPYKASYGVED 121

  Fly   151 PEEATEKLAMTTLRNVAGTHKLMDLLSSKEYLSNQIEGILYNSTEPWGIRVERVEIKEIFMPDQL 215
            ||.|..:||.||:|:..|...|..:...:|.|:..|...:..:.:.||||..|.|||:|.:|.::
  Rat   122 PEYAVTQLAQTTMRSELGKLSLDKVFRERESLNANIVDAINQAADCWGIRCLRYEIKDIHVPPRV 186

  Fly   216 KRALAVEQEAMREAKAKVAAAQGERDA---VTALKEAADIM 253
            |.::.::.||.|..:|.|..::|.|::   |...|:.|.|:
  Rat   187 KESMQMQVEAERRKRATVLESEGTRESAINVAEGKKQAQIL 227

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14644	NP_649445.3	PHB	64..223	CDD:214581	51/161 (32%)
CG14644	NP_649445.3	SPFH_like	89..292	CDD:302763	57/171 (33%)
Stoml2	NP_001026816.1	HflC	38..314	CDD:223407	64/205 (31%)
		SPFH_paraslipin	74..184	CDD:259811	38/109 (35%)
		Band_7_C	259..321	CDD:292817
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	324..353
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0330
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810