Protein Alignment CG14642 and TMPRSS11D

DIOPT Version :9

• Sequence 1: NP_001246901.1
• Gene: CG14642 / 40532
• FlyBaseID: FBgn0037222
• Length: 392
• Species: Drosophila melanogaster
• Sequence 2: NP_004253.1
• Gene: TMPRSS11D / 9407
• HGNCID: 24059
• Length: 418
• Species: Homo sapiens
• Alignment Length: 394
• Identity: 100/394 - (25%)
• Similarity: 155/394 - (39%)
• Gaps: 93/394 - (23%)

  Fly    61 EEKMWFHITDFQFDRVEGPTQ-PKPKPRQYPPPPMPGQPFPPPPGGFKKKENKQRRLCEQKYSEY 124
            ::|.:|:.:.||...||..:| ..|..::|  ..:.|:     ......|..|:..|..|....:
Human    44 DQKSYFYRSSFQLLNVEYNSQLNSPATQEY--RTLSGR-----IESLITKTFKESNLRNQFIRAH 101

  Fly   125 VERIFPNDTAVAADA----------NDADFDGRV------------------------------- 148
            |.::..:.:.|.||.          |.|....|:
Human   102 VAKLRQDGSGVRADVVMKFQFTRNNNGASMKSRIESVLRQMLNNSGNLEINPSTEITSLTDQAAA 166

  Fly   149 ---LARPGEYPHMAAV-------GFESDRG----QVD------YKCGGSLISERFVLTAAHCTSI 193
               :...|..|.:..:       |.|::.|    ||.      :.||||||:..::||||||...
Human   167 NWLINECGAGPDLITLSEQRILGGTEAEEGSWPWQVSLRLNNAHHCGGSLINNMWILTAAHCFRS 231

  Fly   194 YEAPPKWVRIGDLDLASEKRSVEAQLLRIEQVFAHPNYKKKMYYDDIALLKLEKEVELTEYVRPV 258
            ...|..|:....:.....|..     :|:..:..|.|||...:.:||||::||..|..|:.:..|
Human   232 NSNPRDWIATSGISTTFPKLR-----MRVRNILIHNNYKSATHENDIALVRLENSVTFTKDIHSV 291

  Fly   259 RLWVFPEL-----PTTIAFAMGYGATSFAKPMTNRLTNLNLTVVPNAECNAELPPLAETPSGVLE 318
            .|   |..     |.:.|:..|:||..:|......|....:.::.|..|||   |.:.. ..:|.
Human   292 CL---PAATQNIPPGSTAYVTGWGAQEYAGHTVPELRQGQVRIISNDVCNA---PHSYN-GAILS 349

  Fly   319 SQICAQDYILNRDTCQGDSGGPLQLNLPGRRRGHRIHYHLIGITSYGVFC-RSSYPSVYTRVSSF 382
            ..:||.......|.|||||||||.      :...|..:.::||.|:|..| ....|.|||||:::
Human   350 GMLCAGVPQGGVDACQGDSGGPLV------QEDSRRLWFIVGIVSWGDQCGLPDKPGVYTRVTAY 408

  Fly   383 LDWI 386
            ||||
Human   409 LDWI 412

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG14642	NP_001246901.1	Tryp_SPc	146..387	CDD:238113	80/298 (27%)
		Tryp_SPc	146..386	CDD:214473	78/296 (26%)
TMPRSS11D	NP_004253.1	SEA	48..143	CDD:279699	20/101 (20%)
		Tryp_SPc	186..412	CDD:214473	75/243 (31%)
		Tryp_SPc	187..415	CDD:238113	77/244 (32%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X11
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.910