DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG14642 and TMPRSS13

DIOPT Version :9

Sequence 1:NP_001246901.1 Gene:CG14642 / 40532 FlyBaseID:FBgn0037222 Length:392 Species:Drosophila melanogaster
Sequence 2:NP_001070731.1 Gene:TMPRSS13 / 84000 HGNCID:29808 Length:567 Species:Homo sapiens


Alignment Length:266 Identity:73/266 - (27%)
Similarity:114/266 - (42%) Gaps:64/266 - (24%)


- Green bases have known domain annotations that are detailed below.


  Fly   146 GRVLARPGEYPHMAAVGFESDRGQVDYKCGGSLISERFVLTAAHC-----TSIYEAPPKWVRIGD 205
            |..||...::|...::.|.:     .:.|||:||..::|||||||     ..:.|....:....:
Human   328 GGALASDSKWPWQVSLHFGT-----THICGGTLIDAQWVLTAAHCFFVTREKVLEGWKVYAGTSN 387

  Fly   206 LDLASEKRSVEAQLLRIEQVFAHPNYKKKMYYDDIALLKLEKEVELTEYVRPVRL---------- 260
            |....|..|       |.::..:.||..:....||||::|.|.:.|:.::.|..|          
Human   388 LHQLPEAAS-------IAEIIINSNYTDEEDDYDIALMRLSKPLTLSAHIHPACLPMHGQTFSLN 445

  Fly   261 ---WVFPELPTTIAFAMGYGATSFAKPMTNR-LTNLNLTVVPNAECNAELPPLAETPSGVLES-- 319
               |:           .|:|.|......|:. |..:.:.::...:||..|         |.:|  
Human   446 ETCWI-----------TGFGKTRETDDKTSPFLREVQVNLIDFKKCNDYL---------VYDSYL 490

  Fly   320 ---QICAQDYILNRDTCQGDSGGPLQLNLPGRRRGHRIHYHLIGITSYGVFC-RSSYPSVYTRVS 380
               .:||.|....||:|||||||||......|       ::|.|:||:|..| :.:.|.|||:|:
Human   491 TPRMMCAGDLRGGRDSCQGDSGGPLVCEQNNR-------WYLAGVTSWGTGCGQRNKPGVYTKVT 548

  Fly   381 SFLDWI 386
            ..|.||
Human   549 EVLPWI 554

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG14642NP_001246901.1 Tryp_SPc 146..387 CDD:238113 73/266 (27%)
Tryp_SPc 146..386 CDD:214473 71/264 (27%)
TMPRSS13NP_001070731.1 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..115
13 X 5 AA repeats of A-S-P-A-[GLQR] 9..93
4 X 5 AA repeats of T-P-P-G-R 14..68
DUF3682 16..>87 CDD:289231
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 131..157
SRCR_2 231..320 CDD:292133
Tryp_SPc 325..554 CDD:214473 71/264 (27%)
Tryp_SPc 326..557 CDD:238113 73/266 (27%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 1 1.000 - - X11
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
21.910

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