DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG14642 and c1s.2

DIOPT Version :9

Sequence 1:	NP_001246901.1	Gene:	CG14642 / 40532	FlyBaseID:	FBgn0037222	Length:	392	Species:	Drosophila melanogaster
Sequence 2:	NP_001107921.2	Gene:	c1s.2 / 793504	ZFINID:	ZDB-GENE-030131-4645	Length:	458	Species:	Danio rerio

Alignment Length:	297	Identity:	88/297 - (29%)
Similarity:	134/297 - (45%)	Gaps:	64/297 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly   123 EYVERIFPNDTAVAADANDADFD-GRVL----ARPGEYP----HMAAVGFESDRGQVDYKCGGSL 178
            |.:.:|||....|.. .|..|.. |||.    ||.||.|    |.:     |.||      ..:|
Zfish   193 EKLTKIFPKCEPVCG-INMEDLSAGRVFGGKPARSGEIPWQLLHKS-----SPRG------SATL 245

  Fly   179 ISERFVLTAAHCTSIYE-APPKWVRIGDLDLASEKRSVEAQLLRIEQVFAHPNYKK-------KM 235
            ||:.:.||||......| ....|  :|.:..|.:..:|   .:..|::..||||||       ..
Zfish   246 ISDYWALTAASLVDGNENRNMSW--LGGIVNAQDTNAV---FMETEKIIIHPNYKKVDKDGRQSD 305

  Fly   236 YYDDIALLKLEKEVELTEYVRPVRLWVFPE---------LPTTIAFAMGYGATSFAKPMTNRLTN 291
            :.:||||:|:...|.|...:|||.|   |:         :..|::   |:|.  :.:.::..|..
Zfish   306 FNNDIALIKMSAMVPLGPNIRPVCL---PKKTDEAVKEGMMGTVS---GFGV--YGRTVSKLLRY 362

  Fly   292 LNLTVVPNAEC-NAELPPLAETPSGVLESQICAQDYILNRDTCQGDSGGPLQLNLPGRRRGHRIH 355
            .::.|.....| :.:||        |.::..||.|.:...|:|.|||||||...:.|  .|...|
Zfish   363 GHVHVYSLKSCVSGDLP--------VSDNMFCAGDDVHGIDSCSGDSGGPLFFPMLG--DGTEEH 417

  Fly   356 YHLI-GITSYGVFC-RSSYPSVYTRVSSFLDWIELTV 390
            .::: ||.|:|..| ::.....||:|.::|||||.|:
Zfish   418 RYVVKGIVSWGPICAKTITKGYYTKVQNYLDWIEETM 454

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14642	NP_001246901.1	Tryp_SPc	146..387	CDD:238113	78/268 (29%)
CG14642	NP_001246901.1	Tryp_SPc	146..386	CDD:214473	77/267 (29%)
c1s.2	NP_001107921.2	CUB	25..133	CDD:238001
c1s.2	NP_001107921.2	Tryp_SPc	217..450	CDD:214473	76/266 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910