DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG14642 and Cfi

DIOPT Version :9

Sequence 1:	NP_001246901.1	Gene:	CG14642 / 40532	FlyBaseID:	FBgn0037222	Length:	392	Species:	Drosophila melanogaster
Sequence 2:	NP_077071.1	Gene:	Cfi / 79126	RGDID:	620429	Length:	604	Species:	Rattus norvegicus

Alignment Length:	253	Identity:	75/253 - (29%)
Similarity:	110/253 - (43%)	Gaps:	38/253 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly   150 ARPGEYPHMAAVGFESDRGQVDYKCGGSLISERFVLTAAHCT--SIYEAPPKWVRIGDLDLASEK 212
            |..|:||...|:. :.||    ..|||..|...::||||||.  |.|.....|..:.|....:.:
  Rat   368 AEMGDYPWQVAIK-DGDR----ITCGGIYIGGCWILTAAHCVRPSRYRNYQVWTSLLDWLKPNSQ 427

  Fly   213 RSVEAQLLRIEQVFAHPNYKKKMYYDDIALLKL-----EKEVELTEYVRPVRLWVFPEL--PTTI 270
            .:|:.    :.:|..|..|....|.:||||:::     :||.||...|.....| .|.|  |...
  Rat   428 LAVQG----VSRVVVHEKYNGATYQNDIALVEMKKHPGKKECELINSVPACVPW-SPYLFQPNDR 487

  Fly   271 AFAMGYG-ATSFAKPMTNRLTNLNLTVVPNAECNAELPPLAETPSGVLESQI-CAQDYILNRDTC 333
            ....|:| .....|..:.|...::|.    ..|:...      |....|.:: ||.....:.|.|
  Rat   488 CIISGWGREKDNQKVYSLRWGEVDLI----GNCSRFY------PGRYYEKEMQCAGTSDGSIDAC 542

  Fly   334 QGDSGGPLQLNLPGRRRGHRIHYHLIGITSYGVFC-RSSYPSVYTRVSSFLDWIELTV 390
            :|||||||..     :..:.:.| :.||.|:|..| :..:|.|||||:|:.|||...|
  Rat   543 KGDSGGPLVC-----KDVNNVTY-VWGIVSWGENCGKPEFPGVYTRVASYFDWISYYV 594

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14642	NP_001246901.1	Tryp_SPc	146..387	CDD:238113	73/248 (29%)
CG14642	NP_001246901.1	Tryp_SPc	146..386	CDD:214473	72/247 (29%)
Cfi	NP_077071.1	FIMAC	46..111	CDD:214493
		SR	117..220	CDD:214555
		SRCR	122..219	CDD:278931
		LDLa	228..258	CDD:197566
		LDLa	264..298	CDD:294076
		Tryp_SPc	361..590	CDD:214473	72/247 (29%)
		Tryp_SPc	362..591	CDD:238113	73/248 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910