DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG14642 and st14b

DIOPT Version :9

Sequence 1:	NP_001246901.1	Gene:	CG14642 / 40532	FlyBaseID:	FBgn0037222	Length:	392	Species:	Drosophila melanogaster
Sequence 2:	XP_005161261.1	Gene:	st14b / 777629	ZFINID:	ZDB-GENE-061103-613	Length:	864	Species:	Danio rerio

Alignment Length:	313	Identity:	87/313 - (27%)
Similarity:	139/313 - (44%)	Gaps:	65/313 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly   108 KKENKQRRLCEQKYSEYVERIFPNDTAVAADANDADFDGRVLARPGEYPHMAA---VGFESDRGQ 169
            |.:|||   |..|.:...:    .:|.....:::|:      .:.|:.||.::   .|.:||.|:
Zfish   584 KCKNKQ---CISKLNPMCD----GETDCVDGSDEAE------CKCGKKPHKSSRIVGGKDSDEGE 635

  Fly   170 VDYK-----------CGGSLISERFVLTAAHCTS-----IYEAPPKW-VRIGDLDLASEKRSVEA 217
            ..::           ||.|:||..:::|||||..     .|....:| |.:|..:.....:|.:.
Zfish   636 WPWQVSLHMKTQGHVCGASVISNSWLVTAAHCVQDNDQFRYSQADQWEVYLGLHNQGETSKSTQR 700

  Fly   218 QLLRIEQVFAHPNYKKKMYYDDIALLKLEKEVELTEYVRPVRLWVFPELPT------TIAFAMGY 276
            .:|||   ..||.|....|.:||||::|:..|.|.:.:.|:.|   |: ||      ...:..|:
Zfish   701 SVLRI---IPHPQYDHSSYDNDIALMELDSPVTLNQNIWPICL---PD-PTHYFPAGKSVWITGW 758

  Fly   277 GAT---SFAKPMTNRLTNLNLTVVPNAECNAELPPLAETPSGVLESQICAQDYILNRDTCQGDSG 338
            |..   |.|.|..  |....:.::.:..|:..:      ..|:....|||.......|.||||||
Zfish   759 GKLREGSDAVPSV--LQKAEVRIINSTVCSKLM------DDGITPHMICAGVLSGGVDACQGDSG 815

  Fly   339 GPLQLNLPGRRRGHRIHYHLIGITSYGVFC-RSSYPSVYTRVSSFLDWI-ELT 389
            ||:. ::.|..|     ..|.|:.|:|..| |.:.|.|||||:.:..|| |:|
Zfish   816 GPMS-SIEGNGR-----MFLAGVVSWGDGCGRRNRPGVYTRVTDYRSWIREIT 862

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14642	NP_001246901.1	Tryp_SPc	146..387	CDD:238113	77/271 (28%)
CG14642	NP_001246901.1	Tryp_SPc	146..386	CDD:214473	75/269 (28%)
st14b	XP_005161261.1	SEA	92..180	CDD:279699
		CUB	233..342	CDD:238001
		CUB	351..457	CDD:238001
		LDLa	465..497	CDD:238060
		LDLa	499..533	CDD:238060
		LDLa	536..570	CDD:238060
		LDLa	578..613	CDD:238060	8/41 (20%)
		Tryp_SPc	624..858	CDD:214473	72/254 (28%)
		Tryp_SPc	625..861	CDD:238113	74/256 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X11
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.910