DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG14642 and tmprss4

DIOPT Version :9

Sequence 1:	NP_001246901.1	Gene:	CG14642 / 40532	FlyBaseID:	FBgn0037222	Length:	392	Species:	Drosophila melanogaster
Sequence 2:	XP_012822151.1	Gene:	tmprss4 / 733869	XenbaseID:	XB-GENE-940762	Length:	785	Species:	Xenopus tropicalis

Alignment Length:	239	Identity:	69/239 - (28%)
Similarity:	120/239 - (50%)	Gaps:	29/239 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly   154 EYPHMAAVGFESDRGQVDYKCGGSLISERFVLTAAHCTSIYEAP-PKW-VRIGDLDLASEKRSVE 216
            :||...::.:   .||  :.||||:::.|::|.||||....:.. .:| |:.|...|.....:.
Frog   562 KYPWQVSLQY---MGQ--HICGGSILNSRWILCAAHCFDRGQRQVDRWRVQYGITTLTYLFGTF- 620

  Fly   217 AQLLRIEQVFAHPNYKKKMYYDDIALLKLEKEVELTEYVRPVRLWVFPE--LPTTIAFAMGYGAT 279
                 ::::|.:..|......:|||||:|:.::..:..|:||.|..:..  :...:.:..|:|.|
Frog   621 -----VDKIFLNSKYVTDQKPNDIALLQLKSDIVASASVQPVCLPGYDNNLVVGAVLYVTGWGHT 680

  Fly   280 -SFAKPMTNRLTNLNLTVVPNAECNAELPPLAETPSGVLESQICAQDYILNRDTCQGDSGGPLQL 343
             .....:.::|..:.::::.:..||.|.      ...:|::.:||.......||||||||||| :
Frog   681 VEGGAALASQLQEVAISLISSTTCNQEY------GGQILDTMLCAGKIAGGADTCQGDSGGPL-V 738

  Fly   344 NLPGRRRGHRIHYHLIGITSYGVFC-RSSYPSVYTRVSSFLDWI 386
            :|     |...|:..:||.|:|..| |.:...|||.|.|||:||
Frog   739 SL-----GQSSHWEQVGIVSWGDGCGRPNRVGVYTDVQSFLNWI 777

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14642	NP_001246901.1	Tryp_SPc	146..387	CDD:238113	69/239 (29%)
CG14642	NP_001246901.1	Tryp_SPc	146..386	CDD:214473	67/237 (28%)
tmprss4	XP_012822151.1	ATF7IP_BD	<110..233	CDD:293393
		PHA03193	<206..340	CDD:177555
		LDLa	402..434	CDD:238060
		SRCR_2	453..545	CDD:292133
		SRCR	464..541	CDD:278931
		Tryp_SPc	551..777	CDD:214473	67/237 (28%)
		Tryp_SPc	552..777	CDD:238113	67/237 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X11
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.000