DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG14642 and Masp1

DIOPT Version :9

Sequence 1:	NP_001246901.1	Gene:	CG14642 / 40532	FlyBaseID:	FBgn0037222	Length:	392	Species:	Drosophila melanogaster
Sequence 2:	XP_006248588.1	Gene:	Masp1 / 64023	RGDID:	620213	Length:	733	Species:	Rattus norvegicus

Alignment Length:	340	Identity:	89/340 - (26%)
Similarity:	143/340 - (42%)	Gaps:	89/340 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly   114 RRLCEQKY--------------------SEYVERIFPNDTAVAADANDA--DFDGRVL----ARP 152
            |..|:|.|                    :|.::|..|....|....:.|  :...|::    |..
  Rat   399 RYSCQQPYYKMLHNTTGVYTCSAHGTWTNEVLKRSLPTCLPVCGQPSRALPNLVKRIIGGRNAEL 463

  Fly   153 GEYPHMAAVGFESDRGQV--DYKCG-GSLISERFVLTAAHC-----------------TSIYEAP 197
            |.:|..|.:..| |..::  |...| |:|:||.::|||||.                 .::|
  Rat   464 GLFPWQALIVVE-DTSRIPNDKWFGSGALLSESWILTAAHVLRSQRRDNTVIPVSKDHVTVY--- 524

  Fly   198 PKWVRIGDLDLASEKRSVEAQLLRIEQVFAHPNYKKKMYYDDIALLKLEKEVELTEYVRPVRLWV 262
                 :|..|:..:..:|.:...|   |..||::..:.|..||||::|::.|.|..:|.|:.| .
  Rat   525 -----LGLHDVRDKSGAVNSSAAR---VVLHPDFNIQNYNHDIALVQLQEPVPLGAHVMPICL-P 580

  Fly   263 FPE----LPTTIAFAMGYGAT-----------SFAKPMTNRLTNLNLTVVPNAECNAELPPLAET 312
            .||    .|..:....|:|.:           |..:.:::.|..:.|.||.:|||.|..    |:
  Rat   581 RPEPEGPAPHMLGLVAGWGISNPNVTVDEIIISGTRTLSDVLQYVKLPVVSHAECKASY----ES 641

  Fly   313 PSG---VLESQICAQDYILNRDTCQGDSGGPLQLNLPGRRRGHRIHYHLIGITSYG--VFCRSSY 372
            .||   |.|:..||..|...:|||.|||||...:.....:|     :...|:.|:|  ..|.|..
  Rat   642 RSGNYSVTENMFCAGYYEGGKDTCLGDSGGAFVIFDEMSQR-----WVAQGLVSWGGPEECGSKQ 701

  Fly   373 P-SVYTRVSSFLDWI 386
            . .|||:||:::||:
  Rat   702 VYGVYTKVSNYVDWL 716

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14642	NP_001246901.1	Tryp_SPc	146..387	CDD:238113	80/286 (28%)
CG14642	NP_001246901.1	Tryp_SPc	146..386	CDD:214473	79/284 (28%)
Masp1	XP_006248588.1	CUB	33..142	CDD:238001
		FXa_inhibition	158..186	CDD:291342
		CUB	190..299	CDD:278839
		CCP	306..368	CDD:153056
		CCP	372..437	CDD:153056	7/37 (19%)
		Tryp_SPc	454..715	CDD:214473	78/282 (28%)
		Tryp_SPc	455..716	CDD:238113	78/282 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910