DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG14642 and c1s

DIOPT Version :9

Sequence 1:	NP_001246901.1	Gene:	CG14642 / 40532	FlyBaseID:	FBgn0037222	Length:	392	Species:	Drosophila melanogaster
Sequence 2:	XP_002941253.2	Gene:	c1s / 613055	XenbaseID:	XB-GENE-995410	Length:	691	Species:	Xenopus tropicalis

Alignment Length:	303	Identity:	82/303 - (27%)
Similarity:	144/303 - (47%)	Gaps:	64/303 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly   111 NKQRRLCEQKYSEYVERIFPNDTAVAADANDADFDGRVL----ARPGEYPHMAAVGF-ESDRGQV 170
            ||:..:|               |.|.. .:.:|..||:.    |:||::|.|  :.| :.:.|
Frog   416 NKELPIC---------------TPVCG-VHQSDKSGRIFGGTRAKPGQFPWM--IQFTDIELG-- 460

  Fly   171 DYKCGGSLISERFVLTAAHCTSIYEAPPKWVRI----GDLDLASEKRSVEAQLLRIEQVFAHPNY 231
                ||||||:|:||||||..:....|..:..:    .:.:|.|:::.::|     :::..||.|
Frog   461 ----GGSLISDRWVLTAAHVVNKKIFPTMFGGVMKFFPNTNLQSQEKRLQA-----KKIIIHPLY 516

  Fly   232 K-------KKMYYDDIALLKLEKEVELTEYVRPV---RLWVFPELPTTIAFAMGYGATSFAKPMT 286
            :       :..:.:||||::|.|:|:|...:.|:   |..:.| :...:|...|:|.|...:...
Frog   517 QDNEDTEGQSNFDNDIALVQLTKKVKLGSCISPICLPRRGLAP-VVNEVATIAGWGKTEKRESAV 580

  Fly   287 N-RLTNLNLTVVPNAECNAELPPLAETPSGVL-ESQICAQDYILNRDTCQGDSGGPLQLNLPGRR 349
            | :..:::|:.:.  :|..     |....|.. .:.:||...: .:|:|.|||||||....|
Frog   581 NLQFASISLSSMD--KCKK-----ATGGKGYFTPNMLCAGSDV-GKDSCNGDSGGPLMFTDP--- 634

  Fly   350 RGHRIHYHLIGITSYGVFCRSSYPSVYTRVSSFLDWIELTVWA 392
             ......::.||.|:|.....:| .:||:|.::|||||.|:.|
Frog   635 -QDSSKMYMAGIVSWGPRDCGTY-GLYTKVDNYLDWIEETIAA 675

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14642	NP_001246901.1	Tryp_SPc	146..387	CDD:238113	72/261 (28%)
CG14642	NP_001246901.1	Tryp_SPc	146..386	CDD:214473	71/260 (27%)
c1s	XP_002941253.2	CUB	21..131	CDD:238001
		FXa_inhibition	145..173	CDD:405372
		CUB	177..288	CDD:238001
		PHA02927	301..>436	CDD:222943	6/35 (17%)
		Tryp_SPc	436..669	CDD:214473	70/259 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910