DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG14642 and CG18754

DIOPT Version :9

Sequence 1:	NP_001246901.1	Gene:	CG14642 / 40532	FlyBaseID:	FBgn0037222	Length:	392	Species:	Drosophila melanogaster
Sequence 2:	NP_652652.3	Gene:	CG18754 / 59145	FlyBaseID:	FBgn0042106	Length:	341	Species:	Drosophila melanogaster

Alignment Length:	285	Identity:	84/285 - (29%)
Similarity:	126/285 - (44%)	Gaps:	63/285 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly   128 IFPN------DTAVAAD--ANDADFDGRVLARPGEYPHMAAVGFESDRGQVDYKCGGSLISERFV 184
            :.||      .|.|..|  |.:|:.:        |||.|..:.:|:..         |||  |:|
  Fly    90 VLPNKQTCGQTTPVFRDRGAENAELN--------EYPWMVLLLYENRL---------SLI--RYV 135

  Fly   185 LTAAHCT-----SIYEAPPKWVRIGDLD---LASEKRSVEAQLLRIEQVFAHPNYKKK--MYYDD 239
            ||||||.     :..:...|.||:|:..   :.||.|..... :.:.|...|..:...  .|.:|
  Fly   136 LTAAHCVIGGYLTQNDLVLKSVRLGESTTDCITSESRCPHLD-VEVGQTTVHQGFTSSGGTYRND 199

  Fly   240 IALLKLEKEVELTEYVRPVRLW--VFP--ELPTTIAFAMGYGATSFAKPM-TNRLTNLNLTVVPN 299
            ||||:|:..|..|:.::|:.|.  .||  :|...|:   |:..|..::.: |:.:...|     .
  Fly   200 IALLRLQFPVRYTKKIQPICLLDAEFPLQDLNLQIS---GWDPTKSSQTLITSTVKERN-----P 256

  Fly   300 AECNAELPPLAETPSGVLESQICAQDYILNRDTCQGDSGGPLQLNLPGRRRGHRIHYHLIGITSY 364
            |:|      |...||....||:||... ...|||.|.||.|: :.:.|  .|......|.||.||
  Fly   257 ADC------LNRYPSFRSASQVCAGGQ-RKGDTCAGISGSPV-MGIMG--SGVDEFVFLAGIASY 311

  Fly   365 G-VFCRSS-YPSVYTRVSSFLDWIE 387
            | .:|.|: .|.|||::..|.:||:
  Fly   312 GQQYCYSAGIPGVYTKIGHFSEWIK 336

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14642	NP_001246901.1	Tryp_SPc	146..387	CDD:238113	76/257 (30%)
CG14642	NP_001246901.1	Tryp_SPc	146..386	CDD:214473	75/256 (29%)
CG18754	NP_652652.3	CLIP	35..84	CDD:288855
		Tryp_SPc	108..338	CDD:238113	79/267 (30%)
		Tryp_SPc	108..335	CDD:214473	77/264 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.910