DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG14642 and AgaP_AGAP006485

DIOPT Version :9

Sequence 1:	NP_001246901.1	Gene:	CG14642 / 40532	FlyBaseID:	FBgn0037222	Length:	392	Species:	Drosophila melanogaster
Sequence 2:	XP_001688885.1	Gene:	AgaP_AGAP006485 / 5667297	VectorBaseID:	AGAP006485	Length:	281	Species:	Anopheles gambiae

Alignment Length:	255	Identity:	71/255 - (27%)
Similarity:	116/255 - (45%)	Gaps:	51/255 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly   153 GEYPHMAAVGFESDRGQVDYKCGGSLISERFVLTAAHCTSIYEA-----PPKW--VRIGDLDLAS 210
            |::|  :||...:   ..:..|||:::..:.|||||.|  ::.|     .|.|  ||.||:.||.
Mosquito    40 GQFP--SAVSINT---TFNVHCGGAVVDRQHVLTAAQC--VFNANLRLVDPYWITVRAGDIALAP 97

  Fly   211 EKRSVEAQLLRIEQVFAHPNYKKKMYYDDIALLKLEKEVELTEYV-----RPVRLWVFPELP--T 268
            .  ....|..::..:|.||.:..:....|:|:|:|::..:|....     |..|:     :|  .
Mosquito    98 V--GARRQTRKVSHIFVHPQFNIRTLEHDVAVLRLDRPYDLPSNTINLANRTRRI-----VPNGA 155

  Fly   269 TIAFAMGYGATSFA--KPMTNRLTNLNLTVVPNAECNAELPPLAETPSG-VLESQICAQDY--IL 328
            :..|| |:||::.|  .|:......|.:||.....||.     |...:| :|||.:||.:.  ..
Mosquito   156 SCQFA-GWGASTAALNAPVNVLQRFLPMTVNDRDMCNQ-----ANMHAGRMLESHLCAGNTGGSN 214

  Fly   329 NRDTCQGDSGGPLQLNLPGRRRGHRIHYHLIGITSYGVFC-RSSYPSVYTRVSSFLDWIE 387
            |...|.|::|           .|......|:|..|:|:.| .::.|.|:|:|..:.||||
Mosquito   215 NAAPCNGNAG-----------TGLYCERALVGTLSFGLNCGAANNPPVFTQVRFYNDWIE 263

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14642	NP_001246901.1	Tryp_SPc	146..387	CDD:238113	69/253 (27%)
CG14642	NP_001246901.1	Tryp_SPc	146..386	CDD:214473	68/252 (27%)
AgaP_AGAP006485	XP_001688885.1	Tryp_SPc	30..262	CDD:214473	68/252 (27%)
AgaP_AGAP006485	XP_001688885.1	Tryp_SPc	32..265	CDD:238113	71/255 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910