DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG14642 and f10

DIOPT Version :9

Sequence 1:	NP_001246901.1	Gene:	CG14642 / 40532	FlyBaseID:	FBgn0037222	Length:	392	Species:	Drosophila melanogaster
Sequence 2:	NP_001015728.1	Gene:	f10 / 548445	XenbaseID:	XB-GENE-971433	Length:	464	Species:	Xenopus tropicalis

Alignment Length:	308	Identity:	78/308 - (25%)
Similarity:	131/308 - (42%)	Gaps:	56/308 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly   108 KKENKQRRLCE---QKYSEYVERIFPNDTAVAADANDADFD-------------GRVLARPGEYP 156
            |:|.::.:|.|   :.:::....:..|.|....:.|....:             ||..:: ||.|
Frog   177 KRERRETKLHENDKKNHTDSQNEVKMNQTGTLPERNVTGINILNPNDPNVRIVGGRECSQ-GECP 240

  Fly   157 HMAAVGFESDRGQVDYKCGGSLISERFVLTAAHC---TSIYEAPPKWVRIGDLD--LASEKRSVE 216
            ..|.:..:.|.|    .|||:::|..|:||||||   |..::     |.:|:|:  ::....|:.
Frog   241 WQALLVSDEDEG----FCGGTILSREFILTAAHCMNQTKYFK-----VVVGELNTKISEGTESIH 296

  Fly   217 AQLLRIEQVFAHPNYKKKMYYDDIALLKLEKEVELTEYVRPVRLWVFPELPTTI------AFAMG 275
                ::|::..||.:.|..|..|||::||::.:..||.:.|..: ..||....:      |...|
Frog   297 ----KVEKIIMHPRFVKSTYDYDIAVIKLKEAINFTENIIPACI-PDPEFADQVLMNEPDAMVSG 356

  Fly   276 YGATSFAKPMTNRLTNLNLTVVPNAECNAELPPLAETPSGVLESQICAQDYILNRDTCQGDSGGP 340
            :|.........:.|..|.:..:....|.      ..:...:.|:..||......:|.||||||||
Frog   357 FGRIHERGRQASTLQMLQVPYIKRHSCK------ESSTFAITENMFCAGFDTEVKDACQGDSGGP 415

  Fly   341 LQLNLPGRRRGHRIHYHLIGITSYGVFC-RSSYPSVYTRVSSFLDWIE 387
            ......|.       |.:.||.|:|..| |.....|||:||....|::
Frog   416 HVTPFKGT-------YFVTGIVSWGEGCARKGKFGVYTKVSKLHRWLK 456

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14642	NP_001246901.1	Tryp_SPc	146..387	CDD:238113	71/252 (28%)
CG14642	NP_001246901.1	Tryp_SPc	146..386	CDD:214473	70/251 (28%)
f10	NP_001015728.1	GLA	22..84	CDD:214503
		EGF_CA	85..121	CDD:238011
		FXa_inhibition	128..163	CDD:373209
		Tryp_SPc	228..456	CDD:238113	71/255 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X11
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.000