DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG14642 and prss60.2

DIOPT Version :9

Sequence 1:	NP_001246901.1	Gene:	CG14642 / 40532	FlyBaseID:	FBgn0037222	Length:	392	Species:	Drosophila melanogaster
Sequence 2:	NP_001099071.1	Gene:	prss60.2 / 541408	ZFINID:	ZDB-GENE-050320-109	Length:	328	Species:	Danio rerio

Alignment Length:	252	Identity:	84/252 - (33%)
Similarity:	113/252 - (44%)	Gaps:	34/252 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly   146 GRVLARPGEYPHMAAVGFESDRGQVDYKCGGSLISERFVLTAAHCTSIYEAPPKWVRIG-----D 205
            |.|.|..|.:|..  |..:|.| ...:.|||||||..:|||||||..........|.:|     .
Zfish    36 GGVNAPEGSWPWQ--VSLQSPR-YGGHFCGGSLISSEWVLTAAHCLPGVSESSLVVYLGRRTQQG 97

  Fly   206 LDLASEKRSVEAQLLRIEQVFAHPNYKKKMYYDDIALLKLEKEVELTEYVRPVRLWVFPELPT-- 268
            ::.....|:|       .::..|.:|......:|||||:|...|...:|:|||.|.....:.:
Zfish    98 VNTHETSRNV-------AKIIVHSSYNSNTNDNDIALLRLSSAVTFNDYIRPVCLAAQNSVYSAG 155

  Fly   269 TIAFAMGYG--ATSFAKPMTNRLTNLNLTVVPNAECNAELPPLAETPSG-VLESQICAQDYILNR 330
            |.::..|:|  ......|....|....:.||.|..|||:|      .|| |..:.|||......:
Zfish   156 TSSWITGWGDVQAGVNLPAPGILQETMIPVVANDRCNAQL------GSGTVTNNMICAGLAKGGK 214

  Fly   331 DTCQGDSGGPLQLNLPGRRRGHRIHYHLIGITSYGVFCRS-SYPSVYTRVSSFLDWI 386
            ||||||||||:...|       ...:...||||:|..|.. :.|.||||||.:..||
Zfish   215 DTCQGDSGGPMVTRL-------CTVWIQAGITSWGYGCADPNSPGVYTRVSQYQSWI 264

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14642	NP_001246901.1	Tryp_SPc	146..387	CDD:238113	84/252 (33%)
CG14642	NP_001246901.1	Tryp_SPc	146..386	CDD:214473	82/250 (33%)
prss60.2	NP_001099071.1	Tryp_SPc	33..264	CDD:214473	82/250 (33%)
		Tryp_SPc	34..267	CDD:238113	84/252 (33%)
		Somatomedin_B	296..326	CDD:295334
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910