DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG14642 and prss27

DIOPT Version :9

Sequence 1:	NP_001246901.1	Gene:	CG14642 / 40532	FlyBaseID:	FBgn0037222	Length:	392	Species:	Drosophila melanogaster
Sequence 2:	XP_031749235.1	Gene:	prss27 / 496619	XenbaseID:	XB-GENE-5744470	Length:	724	Species:	Xenopus tropicalis

Alignment Length:	289	Identity:	84/289 - (29%)
Similarity:	128/289 - (44%)	Gaps:	71/289 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly   133 TAVAADANDADFDGRVL----ARPGEYPHMAAVGFESDRGQVDYKCGGSLISERFVLTAAHCTSI 193
            |..|.|........|::    |:.|::|..  |.|.::.|   :.|||:|||:::|::||||
Frog    19 TPGATDCGIPLVSSRIMGGQSAQEGQWPWQ--VSFRNNGG---HFCGGTLISKQYVISAAHC--- 75

  Fly   194 YEAPPKWVRIGDLDLASEKRSVEAQL--------------LRIEQVFAHPNYKKKMYYDDIALLK 244
                        ...:|...||.|.|              :.::....:|:|..:....||:|::
Frog    76 ------------FPSSSSASSVTAVLGAYMIDQPDGNQVAIPVQSATNYPSYVNEGDSGDISLVQ 128

  Fly   245 LEKEVELTEYVRPVRLWVFP----ELPTTI-AFAMGYG----ATSFAKPMTNRLTNLNLTVVPNA 300
            |...|..|.|:.||.|   |    ..||.: .:..|:|    ..|...|||  |..:.:.::...
Frog   129 LASPVTFTNYILPVCL---PADTVTFPTGLQCWVTGWGNIASDVSLVSPMT--LQEVAVPLIDAN 188

  Fly   301 ECNAELPPLAETPS-------GVLESQICAQDYILNRDTCQGDSGGPLQLNLPGRRRGHRIHYHL 358
            ||||    |.:||:       .|....|||......:|:|||||||||..:..|:       :.|
Frog   189 ECNA----LYQTPNSYGTSSISVHSDMICAGFINGGKDSCQGDSGGPLVCSSSGQ-------WFL 242

  Fly   359 IGITSYGVFCRSSY-PSVYTRVSSFLDWI 386
            .|:.|:|..|..:| |.|||.:.|:.|||
Frog   243 AGVVSFGEGCGQAYRPGVYTLMPSYTDWI 271

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14642	NP_001246901.1	Tryp_SPc	146..387	CDD:238113	81/276 (29%)
CG14642	NP_001246901.1	Tryp_SPc	146..386	CDD:214473	79/274 (29%)
prss27	XP_031749235.1	Tryp_SPc	34..271	CDD:238113	78/272 (29%)
prss27	XP_031749235.1	Tryp_SPc	420..659	CDD:238113
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X11
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.910