DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG14642 and st14

DIOPT Version :9

Sequence 1:	NP_001246901.1	Gene:	CG14642 / 40532	FlyBaseID:	FBgn0037222	Length:	392	Species:	Drosophila melanogaster
Sequence 2:	XP_012821897.2	Gene:	st14 / 448647	XenbaseID:	XB-GENE-1008784	Length:	845	Species:	Xenopus tropicalis

Alignment Length:	261	Identity:	75/261 - (28%)
Similarity:	121/261 - (46%)	Gaps:	48/261 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly   146 GRVLARPGEYPHMAAVGFESDRGQVDYKCGGSLISERFVLTAAHC-----TSIYEAPPKWVRIGD 205
            |.|.|..||:|...::..:.::    :.||.||:|...:::||||     :..|.....|.....
Frog   607 GGVNADTGEFPWQVSLHVKGNK----HTCGASLVSPTMLISAAHCFQDDQSMRYSDASLWTAYLG 667

  Fly   206 LDLASEKRSVEAQLLRIEQVFAHPNYKKKMYYDDIALLKLEKEVELTEYVRPVRLWVFPELPTTI 270
            |...::..|.:....:|:::.||..:....|.:||::|:|||.|:.|::::|:   ..||  :|.
Frog   668 LHDQAQLNSKDVVERKIKRIMAHIGFNDNTYDNDISVLELEKPVDYTDFIQPI---CIPE--STH 727

  Fly   271 AFAM-------GYGATSFAKPMTNRLTNLNLTVVPNAECN----AELPPLAETPSGVLESQICAQ 324
            .|.:       |:||..........|....:.::...|||    .:|.|          ..:||.
Frog   728 DFPVGKPIWVTGWGALKEGGGAAVILQKAEIRIINQTECNKLLDGQLTP----------RMLCAG 782

  Fly   325 DYILNRDTCQGDSGGPL---QLNLPGRRRGHRIHYHLIGITSYGVFC-RSSYPSVYTRVSSFLDW 385
            ......|.|||||||||   :||       :::  :|.||.|:|..| |.:.|.|||||:...||
Frog   783 FVSGGIDACQGDSGGPLSSVELN-------NKV--YLAGIVSWGEGCARRNKPGVYTRVAMMRDW 838

  Fly   386 I 386
            |
Frog   839 I 839

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14642	NP_001246901.1	Tryp_SPc	146..387	CDD:238113	75/261 (29%)
CG14642	NP_001246901.1	Tryp_SPc	146..386	CDD:214473	73/259 (28%)
st14	XP_012821897.2	SEA	76..167	CDD:396113
		CUB	216..320	CDD:238001
		CUB	328..432	CDD:238001
		LDLa	442..474	CDD:238060
		LDLa	476..511	CDD:238060
		LDLa	513..547	CDD:238060
		LDLa	554..587	CDD:197566
		Tryp_SPc	604..839	CDD:214473	73/259 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X11
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.000