DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG14642 and KLK12

DIOPT Version :9

Sequence 1:NP_001246901.1 Gene:CG14642 / 40532 FlyBaseID:FBgn0037222 Length:392 Species:Drosophila melanogaster
Sequence 2:NP_062544.1 Gene:KLK12 / 43849 HGNCID:6360 Length:254 Species:Homo sapiens


Alignment Length:223 Identity:72/223 - (32%)
Similarity:102/223 - (45%) Gaps:50/223 - (22%)


- Green bases have known domain annotations that are detailed below.


  Fly   173 KCGGSLISERFVLTAAHCT-SIYEAPPKWVRIGDLDLASEKRSVEAQLLRIEQV------FAHPN 230
            :|||.||..|:|||||||: |.|     |||:|:..|        :||...||:      ..||.
Human    46 RCGGVLIDHRWVLTAAHCSGSRY-----WVRLGEHSL--------SQLDWTEQIRHSGFSVTHPG 97

  Fly   231 Y--KKKMYYDDIALLKLEKEVELTEYVRPVRLWVFPELPTTIAFA------MGYGATSFAK-PMT 286
            |  ....:..|:.||:|...|.:|..|:|:      .||...|.|      .|:|.|:..: |..
Human    98 YLGASTSHEHDLRLLRLRLPVRVTSSVQPL------PLPNDCATAGTECHVSGWGITNHPRNPFP 156

  Fly   287 NRLTNLNLTVVPNAECNAELPPLAETPSGVLESQICAQDYILNRDTCQGDSGGPLQLNLPGRRRG 351
            :.|..|||::|.:|.|:...      |..:..:.:||.. :..:|.|||||||||...  |..:|
Human   157 DLLQCLNLSIVSHATCHGVY------PGRITSNMVCAGG-VPGQDACQGDSGGPLVCG--GVLQG 212

  Fly   352 HRIHYHLIGITSYGVFCRSSYPSVYTRV 379
                  |:...|.|...:...|.|||.:
Human   213 ------LVSWGSVGPCGQDGIPGVYTYI 234

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG14642NP_001246901.1 Tryp_SPc 146..387 CDD:238113 72/223 (32%)
Tryp_SPc 146..386 CDD:214473 72/223 (32%)
KLK12NP_062544.1 Tryp_SPc 21..236 CDD:214473 72/223 (32%)
Tryp_SPc 22..236 CDD:238113 72/223 (32%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.910

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