DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG14642 and Tmprss9

DIOPT Version :9

Sequence 1:	NP_001246901.1	Gene:	CG14642 / 40532	FlyBaseID:	FBgn0037222	Length:	392	Species:	Drosophila melanogaster
Sequence 2:	XP_006513905.2	Gene:	Tmprss9 / 432478	MGIID:	3612246	Length:	1342	Species:	Mus musculus

Alignment Length:	339	Identity:	96/339 - (28%)
Similarity:	154/339 - (45%)	Gaps:	66/339 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    75 RVEGPTQPKPKPRQYPPPPMPGQPFPPPPGGFKKKENKQRRLCEQKYSEYVERIFPNDTAVAADA 139
            |.|||.    ..|.......||..|....|....|||.:   |:       :|:..:|     ::
Mouse   392 RCEGPV----TERDLKSGHCPGNVFSCQNGQCVSKENPE---CD-------DRVDCSD-----ES 437

  Fly   140 NDADFD----------GRVL----ARPGEYPHMAAVGFESDRGQVDYKCGGSLISERFVLTAAHC 190
            ::|..|          ||::    |.|||:|...::     |...::.||.::|..|::::||||
Mouse   438 DEAQCDCGWQPAWRSAGRIVGGVEAAPGEFPWQVSL-----RENHEHFCGATIIGARWLVSAAHC 497

  Fly   191 TSIYEAPPKW-VRIGDLDLA-SEKRSVEAQLLRIEQVFAHPNYKKKMYYDDIALLKLEKEVELTE 253
            .:.::.|.:| .:.|.:.|: ||..:|..::|||.:   ||.|.......|:|:|:|.:.:....
Mouse   498 FNEFQDPAQWAAQAGSVHLSGSEASAVRTRVLRIAK---HPAYDADTADFDVAVLELARPLPFGR 559

  Fly   254 YVRPVRL----WVFPELPTTIAFAMGYGATSF-AKPMTNRLTNLNLTVVPNAECNAELPPLAETP 313
            ||:|..|    .|||.....:....||....| .||..  |....:.::..:.|::..      .
Mouse   560 YVQPACLPAATHVFPPGKKCLISGWGYLKEDFLVKPEV--LQKATVELLDQSLCSSLY------G 616

  Fly   314 SGVLESQICAQDYILNR-DTCQGDSGGPLQLNLPGRRRGHRIHYHLIGITSYGVFC-RSSYPSVY 376
            ..:.:..:|| .|:..: |:|||||||||....|..|      :.|.||.|:|:.| .:..|.||
Mouse   617 HSLTDRMVCA-GYLDGKVDSCQGDSGGPLVCEEPSGR------FFLAGIVSWGIGCAEARRPGVY 674

  Fly   377 TRVSSFLDWI-ELT 389
            |||:...||| |:|
Mouse   675 TRVTRLRDWILEVT 688

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14642	NP_001246901.1	Tryp_SPc	146..387	CDD:238113	77/254 (30%)
CG14642	NP_001246901.1	Tryp_SPc	146..386	CDD:214473	75/252 (30%)
Tmprss9	XP_006513905.2	SEA	285..365	CDD:366610
		LDLa	407..442	CDD:238060	11/49 (22%)
		Tryp_SPc	455..684	CDD:214473	74/251 (29%)
		Tryp_SPc	756..984	CDD:214473
		Tryp_SPc	1085..1336	CDD:238113
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910