Protein Alignment CG14642 and LPA

DIOPT Version :9

• Sequence 1: NP_001246901.1
• Gene: CG14642 / 40532
• FlyBaseID: FBgn0037222
• Length: 392
• Species: Drosophila melanogaster
• Sequence 2: NP_005568.2
• Gene: LPA / 4018
• HGNCID: 6667
• Length: 2040
• Species: Homo sapiens
• Alignment Length: 443
• Identity: 117/443 - (26%)
• Similarity: 164/443 - (37%)
• Gaps: 119/443 - (26%)

  Fly    16 WCLSNTHTQRLPPEGRMRPLQDDSIRSPVDRDIVFPELDAGPG----KPEEKMWFHITDFQFDRV 76
            |.....|..:..||.    ..:|.:.....|:   |:.|.||.    .|..: |.:....:....
Human  1640 WSSMTPHRHQRTPEN----YPNDGLTMNYCRN---PDADTGPWCFTMDPSIR-WEYCNLTRCSDT 1696

  Fly    77 EGPTQPKPKPRQYP---PPPMPGQPFPPPPG--GFKKKENKQRRLCEQ-------KYSEYVERIF 129
            ||.....|...|.|   ||......|....|  | ||........|::       ::|.::
Human  1697 EGTVVAPPTVIQVPSLGPPSEQDCMFGNGKGYRG-KKATTVTGTPCQEWAAQEPHRHSTFI---- 1756

  Fly   130 PNDTAVAA-DAN-----DADFDG--------RVLARPGEYPHMAAVGFESDRGQVDYK------- 173
            |.....|. :.|     |.|.:|        |.|....:.|..|:..|:..:.||:.|
Human  1757 PGTNKWAGLEKNYCRNPDGDINGPWCYTMNPRKLFDYCDIPLCASSSFDCGKPQVEPKKCPGSIV 1821

  Fly   174 ------------------------CGGSLISERFVLTAAHCTSIYEAPPKW-VRIG---DLDLAS 210
                                    |||:|||..:|||||||......|..: |.:|   :::|.|
Human  1822 GGCVAHPHSWPWQVSLRTRFGKHFCGGTLISPEWVLTAAHCLKKSSRPSSYKVILGAHQEVNLES 1886

  Fly   211 EKRSVEAQLLRIEQVFAHPNYKKKMYYDDIALLKLEKEVELTEYVRPVRLWVFPELPTTI---AF 272
            ..:.:|...|.:|...|           |||||||.:...:|:.|.|..| ..|:...|.   .:
Human  1887 HVQEIEVSRLFLEPTQA-----------DIALLKLSRPAVITDKVMPACL-PSPDYMVTARTECY 1939

  Fly   273 AMGYGAT--SFAKPMTNRLTNLNLTVVPNAECNAELPPLAETPSGVLESQICAQDYILNRDTCQG 335
            ..|:|.|  :|.   |..|....|.|:.|..||.             ...|||:......|:|||
Human  1940 ITGWGETQGTFG---TGLLKEAQLLVIENEVCNH-------------YKYICAEHLARGTDSCQG 1988

  Fly   336 DSGGPLQLNLPGRRRGHRIHYHLIGITSYGVFC-RSSYPSVYTRVSSFLDWIE 387
            ||||||..       ..:..|.|.|:||:|:.| |.:.|.||.|||.|:.|||
Human  1989 DSGGPLVC-------FEKDKYILQGVTSWGLGCARPNKPGVYARVSRFVTWIE 2034

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG14642	NP_001246901.1	Tryp_SPc	146..387	CDD:238113	84/289 (29%)
		Tryp_SPc	146..386	CDD:214473	83/288 (29%)
LPA	NP_005568.2	Kringle	28..105	CDD:278480
		Kringle	142..219	CDD:278480
		Kringle	256..333	CDD:278480
		Kringle	370..447	CDD:278480
		Kringle	484..561	CDD:278480
		Kringle	598..675	CDD:278480
		Kringle	712..789	CDD:278480
		Kringle	826..903	CDD:278480
		KR	938..1019	CDD:214527
		Kringle	1054..1131	CDD:278480
		KR	1166..1246	CDD:214527
		KR	1272..1352	CDD:214527
		KR	1386..1466	CDD:214527
		KR	1500..1581	CDD:214527
		KR	1614..1695	CDD:214527	12/62 (19%)
		Kringle	1720..1799	CDD:278480	16/83 (19%)
		Tryp_SPc	1820..2034	CDD:238113	75/248 (30%)
		Tryp_SPc	1820..2033	CDD:214473	74/247 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910