DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG14642 and ndl

DIOPT Version :9

Sequence 1:	NP_001246901.1	Gene:	CG14642 / 40532	FlyBaseID:	FBgn0037222	Length:	392	Species:	Drosophila melanogaster
Sequence 2:	NP_523947.2	Gene:	ndl / 38738	FlyBaseID:	FBgn0002926	Length:	2616	Species:	Drosophila melanogaster

Alignment Length:	308	Identity:	83/308 - (26%)
Similarity:	141/308 - (45%)	Gaps:	56/308 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly   100 PPPPGGFKKKENKQRRLCEQKYSEYVERIFPNDTAVAADANDADFDGRVLARPGEY------PHM 158
            ||...|...|.:.      .::|:.|.|       ..:|:.:...|||::.  |.|      |.:
  Fly  1110 PPMQCGLPSKSSM------LEHSKRVRR-------AVSDSKEIVGDGRIVG--GSYTSALQWPFV 1159

  Fly   159 AAVGFESDRGQVDYKCGGSLISERFVLTAAHCTSIYEAPPKWVRIGDLDLASEKRSVEAQLLRIE 223
            .|: :.:.:    :.|||::.|:|::::||||...|......||.|.|..:|  .|...|:..:.
  Fly  1160 VAI-YRNGK----FHCGGTIYSDRWIISAAHCVINYGKYFYEVRAGLLRRSS--YSPATQIQPVS 1217

  Fly   224 QVFAHPNYKKKMYYDDIALLKLEKEVELTEYVRPVRL-----------WVFPELPTTIAFAMGYG 277
            .|..|..|:::...:|::||:|...::...:|:|:.|           |::..:..|:...:|:|
  Fly  1218 HVVVHQAYERRSMRNDLSLLRLLNPLQFNRWVKPICLPDKGRTTVGDDWIWGPVEHTLCTVVGWG 1282

  Fly   278 ATSFAKPMTNRLTNLNLTVVP-NAECNAELPPLAETPSGVLESQICAQDYILNRDTCQGDSGGPL 341
            |.....|.::.:..:   :|| ..:|.        .|.......|||.|....||.|||||||||
  Fly  1283 AIREKGPSSDPMRQV---IVPIRKKCT--------DPEDQASEDICAGDPDGGRDACQGDSGGPL 1336

  Fly   342 QLNLPGRRRGHRIHYHLIGITSYGVFC-RSSYPSVYTRVSSFLDWIEL 388
            ..    |...:...::|.|:.|:|..| |.....|||||:.:|||:|:
  Fly  1337 FC----RSVSNPDEFYLAGVVSHGNGCARPQEFGVYTRVTLYLDWLEM 1380

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14642	NP_001246901.1	Tryp_SPc	146..387	CDD:238113	73/259 (28%)
CG14642	NP_001246901.1	Tryp_SPc	146..386	CDD:214473	72/258 (28%)
ndl	NP_523947.2	LDLa	891..927	CDD:238060
		Tryp_SPc	1144..1377	CDD:214473	70/256 (27%)
		Tryp_SPc	1145..1379	CDD:238113	71/257 (28%)
		LDLa	1399..1430	CDD:238060
		Metaviral_G	1448..1600	CDD:118131
		LDLa	1710..1743	CDD:238060
		LDLa	1776..1811	CDD:238060
		DUF1986	2041..2158	CDD:286432
		LDLa	2309..2339	CDD:197566
		LDLa	2350..2383	CDD:197566
		LDLa	2421..2457	CDD:238060
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24258
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	1.100