DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG14642 and CG1299

DIOPT Version :9

Sequence 1:	NP_001246901.1	Gene:	CG14642 / 40532	FlyBaseID:	FBgn0037222	Length:	392	Species:	Drosophila melanogaster
Sequence 2:	NP_647862.1	Gene:	CG1299 / 38496	FlyBaseID:	FBgn0035501	Length:	511	Species:	Drosophila melanogaster

Alignment Length:	339	Identity:	97/339 - (28%)
Similarity:	148/339 - (43%)	Gaps:	84/339 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    77 EGPTQPKPKPRQYPPPPMPGQPFPPPPGGFKKKENKQRRL------CEQKYSEYVERIFPNDTAV 135
            :|.|...|.|.|..|               |..:...|||      |..... |.::|.
  Fly   220 QGITNTTPAPSQIVP---------------KNTDEIPRRLLNVEEGCGSTVG-YFKKIV------ 262

  Fly   136 AADANDADFDGRVLARPGEYPHMAAVGFESDRGQVDYKCGGSLISERFVLTAAHCTSIYEAPPKW 200
                      |..::|.|.:|.:|.:|::...|. .:||||:||:.|.|||||||   .....::
  Fly   263 ----------GGEVSRKGAWPWIALLGYDDPSGS-PFKCGGTLITARHVLTAAHC---IRQDLQF 313

  Fly   201 VRIGDLDLASEKRSVEAQLLRIEQVFAHPNYKKKMYYDDIALLKLEKEVELTEYVRPVRLWVFPE 265
            ||:|:.||:::..:.... :.|.:..:||:|.::....|:|:|.||:.||.|..:.|:.
  Fly   314 VRLGEHDLSTDTETGHVD-INIARYVSHPDYNRRNGRSDMAILYLERNVEFTSKIAPIC------ 371

  Fly   266 LPTT-----------IAFAMGYGATSFAKPMTNRLTNLNLTVVPNAEC-----------NAELPP 308
            ||.|           :.|..|:|.|.........|..|.:.:..|..|           :|:...
  Fly   372 LPHTANLRQKSYVGYMPFVAGWGKTMEGGESAQVLNELQIPIYDNKVCVQSYAKEKRYFSADQFD 436

  Fly   309 LAETPSGVLESQICAQDYILNRDTCQGDSGGPLQLNLPGRRRGHRIHYHLIGITSYGVFC-RSSY 372
            .|...:|||..         .:|||||||||||.  ||...:| ::.::|||:.|||:.| |.:.
  Fly   437 KAVLCAGVLSG---------GKDTCQGDSGGPLM--LPEPYQG-QLRFYLIGVVSYGIGCARPNV 489

  Fly   373 PSVYTRVSSFLDWI 386
            |.||:....|:|||
  Fly   490 PGVYSSTQYFMDWI 503

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14642	NP_001246901.1	Tryp_SPc	146..387	CDD:238113	84/264 (32%)
CG14642	NP_001246901.1	Tryp_SPc	146..386	CDD:214473	82/262 (31%)
CG1299	NP_647862.1	CLIP	37..93	CDD:197829
		CLIP	164..216	CDD:288855
		Tryp_SPc	260..503	CDD:214473	83/281 (30%)
		Tryp_SPc	261..503	CDD:238113	83/280 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X11
	2	1.910