Protein Alignment CG14642 and KLK1

DIOPT Version :9

• Sequence 1: NP_001246901.1
• Gene: CG14642 / 40532
• FlyBaseID: FBgn0037222
• Length: 392
• Species: Drosophila melanogaster
• Sequence 2: NP_002248.1
• Gene: KLK1 / 3816
• HGNCID: 6357
• Length: 262
• Species: Homo sapiens
• Alignment Length: 244
• Identity: 74/244 - (30%)
• Similarity: 119/244 - (48%)
• Gaps: 58/244 - (23%)

  Fly   172 YKCGGSLISERFVLTAAHCTS-IYEAPPKWVRIGDLDLASEKRSVEAQLLRIEQVFAHPNYKKKM 235
            ::|||.|:..::|||||||.| .|:.   |  :|..:|..::.:  ||.:.:.:.|.||.:...:
Human    48 FQCGGILVHRQWVLTAAHCISDNYQL---W--LGRHNLFDDENT--AQFVHVSESFPHPGFNMSL 105

  Fly   236 -----------YYDDIALLKLEKEVE-LTEYVRPVRLWVFPELPT------TIAFAMGYGA---T 279
                       |..|:.||:|.:..: :|:.|:.|      ||||      :...|.|:|:   .
Human   106 LENHTRQADEDYSHDLMLLRLTEPADTITDAVKVV------ELPTEEPEVGSTCLASGWGSIEPE 164

  Fly   280 SFAKPMTNRLTNLNLTVVPNAEC-NAELPPLAETPSGVLESQICAQDYILNRDTCQGDSGGPLQL 343
            :|:.|  :.|..::|.::||.|| .|.:       ..|.:..:|.......:|||.|||||||..
Human   165 NFSFP--DDLQCVDLKILPNDECKKAHV-------QKVTDFMLCVGHLEGGKDTCVGDSGGPLMC 220

  Fly   344 NLPGRRRGHRIHYHLIGITSYG-VFCRS-SYPSVYTRVSSFLDWIELTV 390
            :           ..|.|:||:| |.|.: :.|||..||.|::.|||.|:
Human   221 D-----------GVLQGVTSWGYVPCGTPNKPSVAVRVLSYVKWIEDTI 258

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG14642	NP_001246901.1	Tryp_SPc	146..387	CDD:238113	71/239 (30%)
		Tryp_SPc	146..386	CDD:214473	70/238 (29%)
KLK1	NP_002248.1	Tryp_SPc	25..257	CDD:238113	73/241 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910