DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG14642 and Tmprss4

DIOPT Version :9

Sequence 1:	NP_001246901.1	Gene:	CG14642 / 40532	FlyBaseID:	FBgn0037222	Length:	392	Species:	Drosophila melanogaster
Sequence 2:	XP_038937788.1	Gene:	Tmprss4 / 367074	RGDID:	1305033	Length:	478	Species:	Rattus norvegicus

Alignment Length:	250	Identity:	84/250 - (33%)
Similarity:	125/250 - (50%)	Gaps:	36/250 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly   146 GRVLARPGEYPHMAAVGFESDRGQVDYKCGGSLISERFVLTAAHCTSIYEAPPKW-VRIGDLDLA 209
            |.|.|....:|...::.:..     .:.||||::...::||||||...|.....| ||.|...|.
  Rat   248 GGVEASADSWPWQVSIQYNK-----QHVCGGSILDHHWILTAAHCFRKYLDVSSWKVRAGSNKLG 307

  Fly   210 SEKRSVEAQLLRIEQVF-AHPN---YKKKMYYDDIALLKLEKEVELTEYVRPVRLWVFPE--LPT 268
            :      :..|.:.::| |.||   .|:|    ||||:||:..:..:..|||:.|....|  :||
  Rat   308 N------SPSLPVAKIFIAEPNPLQPKEK----DIALVKLKMPLTFSGSVRPICLPFSDEELIPT 362

  Fly   269 TIAFAMGYGAT-SFAKPMTNRLTNLNLTVVPNAECNAELPPLAETPSGVLESQICAQDYILNRDT 332
            ...:.:|:|.| .....|::.|...::.|:.:|.||||.....|..:|:|    ||......:||
  Rat   363 MPVWVIGWGFTEENGGKMSDTLLQASVQVIDSARCNAEDAYQGEVTAGML----CAGTPQGGKDT 423

  Fly   333 CQGDSGGPLQLNLPGRRRGHRIHYHLIGITSYGVFCRS-SYPSVYTRVSSFLDWI 386
            |||||||||..        |...:.::||.|:|..|.| |.|.|||:|:::||||
  Rat   424 CQGDSGGPLMY--------HYDKWQVVGIVSWGYGCGSPSTPGVYTKVTAYLDWI 470

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14642	NP_001246901.1	Tryp_SPc	146..387	CDD:238113	83/249 (33%)
CG14642	NP_001246901.1	Tryp_SPc	146..386	CDD:214473	82/248 (33%)
Tmprss4	XP_038937788.1	LDLa	99..133	CDD:238060
		SRCR_2	149..238	CDD:413346
		Tryp_SPc	245..470	CDD:214473	82/248 (33%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X11
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.910