DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG14642 and CG30371

DIOPT Version :9

Sequence 1:	NP_001246901.1	Gene:	CG14642 / 40532	FlyBaseID:	FBgn0037222	Length:	392	Species:	Drosophila melanogaster
Sequence 2:	NP_610370.1	Gene:	CG30371 / 35806	FlyBaseID:	FBgn0050371	Length:	399	Species:	Drosophila melanogaster

Alignment Length:	250	Identity:	86/250 - (34%)
Similarity:	126/250 - (50%)	Gaps:	32/250 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly   150 ARPGEYPHMAAVGFESDRGQVDYKCGGSLISERFVLTAAHCTSIYE---APPKWVRIGDLDLASE 211
            |...|:|.|||:. :..:.|..: |||::::.|::||||||  ||:   |......:|..||.:.
  Fly   156 AAANEFPSMAALK-DVTKNQASF-CGGTIVAHRYILTAAHC--IYQVSRATNIVAIVGTNDLGNP 216

  Fly   212 KRSVEAQLLRIEQVFAHPNY-KKKMYYDDIALLKLEKEVELTEYVRPVRLWVFPELPTTIAF--- 272
            ..|...|...|:|:..|..| ......:|||:|.....::.:..|.|:.|   |.:.|:..|
  Fly   217 SSSRYYQQYNIQQMIPHEQYVSDPDVNNDIAVLITASNIQWSRGVGPICL---PPVGTSTPFTYD 278

  Fly   273 ---AMGYGATSFAKPMTNRLTNLNLTVVPNAECNAELPPLAETPSGVLESQICAQDYI-LNRDTC 333
               .:|||...||.|.:..|..:||.||.|.:|..|...:|...:|    |:|..||. ..||:|
  Fly   279 LVDVIGYGTVFFAGPTSTSLQKINLNVVTNQDCQTEYNNVATIYTG----QMCTYDYSGTGRDSC 339

  Fly   334 QGDSGGPLQLNLPGRRRGHRIHYHLIGITSYGVFC-RSSYP-SVYTRVSSFLDWI 386
            |.|||||:.|     |:..:.   |:||.|||..| .|.|| .|.||::|::.||
  Fly   340 QFDSGGPVIL-----RKSRQF---LVGIISYGKSCAESQYPMGVNTRITSYISWI 386

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14642	NP_001246901.1	Tryp_SPc	146..387	CDD:238113	85/249 (34%)
CG14642	NP_001246901.1	Tryp_SPc	146..386	CDD:214473	84/248 (34%)
CG30371	NP_610370.1	CUB	24..>67	CDD:294042
		Tryp_SPc	149..386	CDD:214473	84/248 (34%)
		Tryp_SPc	150..389	CDD:238113	85/249 (34%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45455974
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24258
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.940