DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG14642 and CG14760

DIOPT Version :9

Sequence 1:	NP_001246901.1	Gene:	CG14642 / 40532	FlyBaseID:	FBgn0037222	Length:	392	Species:	Drosophila melanogaster
Sequence 2:	NP_610366.1	Gene:	CG14760 / 35802	FlyBaseID:	FBgn0033277	Length:	529	Species:	Drosophila melanogaster

Alignment Length:	318	Identity:	93/318 - (29%)
Similarity:	135/318 - (42%)	Gaps:	62/318 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    89 YP-PPPMPGQPFPPPPGGFKKKENKQRRLCEQKYSEYVERIFPNDTA-------VAADANDADFD 145
            || ..|.||.      ||             .::|..||...|..:.       :|:..|:.
  Fly   240 YPTAAPSPGH------GG-------------GRFSCLVEAFQPTCSCGWSRIPRIASPTNEE--- 282

  Fly   146 GRVLARPGEYPHMAAVGFESDRGQVDYKCGGSLISERFVLTAAHC---TSIYEAPPKWVRIGDLD 207
                |...|:|.||.| .....|:|  .||.::|..|::|:||||   .....|....|.:|:.|
  Fly   283 ----AVLHEFPPMAGV-LTKKHGKV--FCGAAIIHHRYLLSAAHCFLGPETNSAAKLRVVVGEHD 340

  Fly   208 LASEKRSVEAQLLRIEQVFAHPNYKKK--MYYDDIALLKLEKEVELTEYVRPVRLWVFP-----E 265
            |||...:...|...::.:..|.::.:.  ...:|||:||....:..:::|.|..|.:.|     :
  Fly   341 LASSFETFATQRYDLDALILHEDFSQASGQPKNDIAMLKTRMAIVWSQHVGPACLPLQPGEDGQK 405

  Fly   266 LPTT--IAFAMGYGATSFAKPMTNRLTNLNLTVVPNAECNAELPPLAETPSGVLESQICAQDYIL 328
            ||..  ...|.|:|.||:..|.|:||....|.|:....|...|    .:..|:.....|.  |..
  Fly   406 LPLAGHQVVAAGWGTTSYGGPQTHRLLKATLDVIDGRRCRQAL----SSAGGLPPHTFCT--YTP 464

  Fly   329 NRDTCQGDSGGPLQLNLPGRRRGHRIHYHLIGITSYGVFCRSSYPSVYTRVSSFLDWI 386
            .|||||.||||.|...:.||...       :||.|:|..|.:..|||.|||:||:.||
  Fly   465 GRDTCQYDSGGALYERINGRLMA-------VGIVSFGQACAAQQPSVNTRVASFIKWI 515

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14642	NP_001246901.1	Tryp_SPc	146..387	CDD:238113	80/253 (32%)
CG14642	NP_001246901.1	Tryp_SPc	146..386	CDD:214473	78/251 (31%)
CG14760	NP_610366.1	CUB	37..126	CDD:294042
		Tryp_SPc	281..516	CDD:238113	80/258 (31%)
		Tryp_SPc	281..515	CDD:214473	78/256 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45455979
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24258
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.940